Annals of human genetics

Ann Hum Genet · ISSN (e) 1469-1809 · 4 papers in corpus
observational 2019
doi:10.1111/ahg.12309 ·PMID:30887509

The STAT4 gene is vital to signaling pathways in the immune response. Immunological alterations are involved in the pathogenesis of endometriosis, and STAT4 polymorphisms may be linked to disease development. This study's aim is to evaluate…

observational 2016
doi:10.1111/ahg.12139 ·PMID:26612412

Congenital heart defects (CHDs) develop through a complex interplay between genetic variants, epigenetic modifications, and maternal environmental exposures. Genetic studies of CHDs have commonly tested single genetic variants for associati…

meta-analysis 2013
doi:10.1111/ahg.12048 ·PMID:24308758

A relationship between endometriosis and tumor necrosis factor (TNF-α) and interleukin-6 (IL-6) gene polymorphisms has been raised for Asians. However, this topic is controversial. This study was a meta-analysis to explore whether TNF-α/IL-…

meta-analysis 2012
doi:10.1111/j.1469-1809.2012.00726.x ·PMID:23061744

Published data on the association between the vascular endothelial growth factor (VEGF) gene -460C/T (rs833061), +405G/C (rs2010963), +936T/C (rs3025039) polymorphisms and endometriosis risk are inconclusive. Eleven eligible case-control st…