Anna Szóstek-Mioduchowska

No ORCID on file · 11 papers in corpus · active 2019-2026

Study types

  • other 10
  • article 1

Condition tags

  • endometriosis 9
  • infertility 3
  • disambig:endometritis 2
other 2026
Theriogenology ·doi:10.1016/j.theriogenology.2025.117680

Equine endometrosis is a chronic degenerative condition with fibrosis being one of the most significant characteristics. A growing body of evidence indicates the critical role of interleukin (IL)-17 in fibrotic disorders. However, its exact…

article 2026
·doi:10.1007/s00441-026-04049-6

Fibrosis remains incompletely understood, particularly in terms of how immune mediators shape stromal programs. We used a spontaneous large‑animal model—endometrosis (equine endometrial fibrosis) to define how interleukin‑4 (IL‑4) reprogram…

other 2025
Scientific reports ·doi:10.1038/s41598-025-20152-0

Mare endometrosis is a chronic degenerative condition of the endometrium, primarily characterized by fibrosis, involving interactions among fibroblasts, immune cells, and epithelial cells regulated by cytokines and growth factors. T helper …

other 2025
Reproductive biology ·doi:10.1016/j.repbio.2025.101018

The role of AREG in the development of fibrosis in the progression of endometrosis in mare remains unknown. We aimed to determine the effects of AREG on fibroblast functional characteristics as well as the expression of extracellular matrix…

other 2025
Scientific reports ·doi:10.1038/s41598-025-86742-0

Mares with endometrosis exhibit histological changes not only in the endometrium but also in the myometrium that suggest possible functional impairment. The molecular background of these changes is not well understood. We hypothesize that t…

other 2024
Reproductive biology ·doi:10.1016/j.repbio.2024.100962

A reduction in myometrial contractile activity can lead to inadequate cleaning of the uterine lumen, resulting in persistent endometritis and potentially endometrosis in mares. Oxytocin (OXT) is a key hormonal regulator of myometrial contra…

other 2024
BMC veterinary research ·doi:10.1186/s12917-024-04384-2

BACKGROUND: Endometrosis (chronic degenerative endometritis) results in morphological changes in the equine endometrium and impairs its secretory function. However, the effect of this condition on the myometrium remains unclear. Lysophospha…

other 2022
Animals : an open access journal from MDPI ·doi:10.3390/ani12141854

Collagen pathological deposition in equine endometrium (endometrosis) is responsible for infertility. Kenney and Doig's endometrial biopsy histopathological classification is the gold standard method for endometrosis evaluation, whereby blo…

other 2021
International journal of molecular sciences ·doi:10.3390/ijms22105333

Endometrosis is a reproductive pathology that is responsible for mare infertility. Our recent studies have focused on the involvement of neutrophil extracellular traps enzymes, such as elastase (ELA), in the development of equine endometros…

other 2020
Scientific reports ·doi:10.1038/s41598-020-58109-0

Equine endometrial fibrosis (endometrosis) is described as a degenerative chronic condition in the uterus. Its characteristic feature is excessive deposition of extracellular matrix (ECM) components around the endometrial glands and stroma.…

other 2019
Domestic animal endocrinology ·doi:10.1016/j.domaniend.2018.10.004

Prostaglandin E2 (PGE2) has contradictory effects in many organs. It may have proinflammatory, anti-inflammatory, or anti-fibrotic roles, depending on the type of receptors to which it binds. By signaling through its receptors EP2 and EP4, …