The effect of amphiregulin on equine endometrial fibroblasts: in vitro responses of fibroblast derived from non-fibrotic and fibrotic endometrium
other
OA: hybrid
CC-BY-4.0
AI-generated summary
This study investigated amphiregulin's effects on equine endometrial fibroblasts from non-fibrotic and fibrotic tissue, finding that AREG-regulated ECM remodeling mechanisms might be disrupted in fibrosis.
One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works
Abstract
The role of AREG in the development of fibrosis in the progression of endometrosis in mare remains unknown. We aimed to determine the effects of AREG on fibroblast functional characteristics as well as the expression of extracellular matrix (ECM)-associated genes in fibroblast derived from non-fibrotic and fibrotic equine endometria. Our findings suggest that the mechanisms associated with ECM remodeling regulated by AREG in non-fibrotic fibroblasts may be dysregulated in the progression of fibrosis in endometrosis.
My notes (saved in your browser only)
Condition tags
MeSH descriptors
Citation neighborhood (no data yet)
We don't have any in-corpus citations linked to this paper yet. This is a recent paper (2025) — citers typically take a year or two to land, and the OpenAlex reference graph may still be filling in.
Source provenance
- europepmc
- last seen: 2026-08-30T09:23:35.175841+00:00
- pubmed
- last seen: 2026-08-30T06:05:10.212010+00:00
- unpaywall
- last seen: 2026-05-11T08:34:28.763810+00:00
License: CC-BY-4.0
· commercial use OK
· attribution required
Courtesy of the U.S. National Library of Medicine
Courtesy of the U.S. National Library of Medicine