Julian Matthias Metzler

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OBJECTIVE: To systematically evaluate the clinical evidence on intraoperative navigation techniques in endometriosis surgery. DATA SOURCES: In accordance with the PRISMA guidelines, a systematic literature search was conducted in the datab…

Endometriosis is a chronic inflammatory disease associated with substantial impairment of quality of life. Although the #ENZIAN classification enables detailed anatomical characterization of disease distribution, its relevance for predictin…

INTRODUCTION: Many women with endometriosis turn to digital sources for information. Meanwhile, large language models (LLMs) appear capable of offering health advice. This study aimed to evaluate the potential in answering endometriosis-rel…

PURPOSE: The surgical treatment of endometriosis, which is routinely performed by minimally invasive approach, is developing towards an increasing complexity in deep endometriosis. While RAS appears to be gaining importance, there are few r…

Endometriosis, a disease affecting about one out of ten women, is characterized by the growth of endometrial-like tissue outside the uterine cavity. There is significant disease heterogeneity, but the pathophysiological mechanisms underlyin…

Endometriosis, a disease affecting about one out of ten women, is characterized by the growth of endometrial-like tissue outside the uterine cavity. There is significant disease heterogeneity, but the pathophysiological mechanisms underlyin…

Endometriosis is a chronic inflammatory condition marked by the presence of endometrial-like tissue outside the uterus, often co-occurring with leiomyoma and presenting a diagnostic challenge. We analyzed 96 plasma cytokines and inflammator…

Endometriosis is a chronic inflammatory condition marked by the presence of endometrial-like tissue outside the uterus, often co-occurring with leiomyoma and presenting a diagnostic challenge. We analyzed 96 plasma cytokines and inflammator…

STUDY QUESTION: Is there an association between pre-operative symptoms and intraoperatively described localization and size of endometriosis lesions as assessed by the #ENZIAN classification system? SUMMARY ANSWER: Dyschezia is associated …

Study question: Is there an association between pre-operative symptoms and intraoperatively described localization and size of endometriosis lesions as assessed by the #ENZIAN classification system? Summary answer: Dyschezia is associated w…

Abstract Study question Can we predict peritoneal endometriosis (PE) in women with pain symptoms who have no signs of endometriosis on examination or imaging studies? Summary answer A calculated score including dysmenorrhea, dysuria, dyspar…

Zusammenfassung Endometriose ist eine komplexe Erkrankung mit oft verzögerter Diagnosestellung. Aktuelle Entwicklungen in der sonographischen Bildgebung haben das Potenzial, die Diagnostik erheblich zu verbessern. Die transvaginale Sonograp…

The aim of this review is to analyse the progression of endometriosis research from 2007 to 2022. The PubMed database was searched for publications with titles containing the keyword endometriosis, being created in January and July of the y…

Journal Article Reply: Strengthening patient education on endometriosis therapies Get access N Thurnherr, N Thurnherr Department of Gynecology, University Hospital Zurich, Zurich, Switzerland Correspondence address. Department of Gynecology…

We present a new systematic, comprehensive, checklist-based sonographic assessment of endometriosis in the female true pelvis. Emphasis is placed on practical skills teaching. The newly introduced White Sliding Line (WSL) is the core struct…

STUDY QUESTION: What are the attitudes and perceptions towards endocrine endometriosis therapy? SUMMARY ANSWER: Among the study population, endocrine endometriosis therapies are associated with negative mental images and emotions and there…

OBJECTIVE: Primary aim of this study was to investigate endometriosis characteristics of patients with psychiatric conditions or depression. The secondary aim was to study tolerability of dienogest in this context. METHODS: This observatio…

Background: This study examines endometriosis (EM) features in women with EM and migraines (MG) (EM-MG) and women with EM alone (EM-O). The comorbidity of MG and EM is well known. However, knowledge about differences in symptoms, clinical m…

INTRODUCTION: Endometriosis is a common disabling pain condition in women of childbearing age, frequently showing familial clustering. Nevertheless, little is known about whether familial predispositions influence its severity or presentati…

BACKGROUND: There is a growing body of human, animal and in vitro studies on vitamin D (vit D) substitution in endometriosis. The aim of this systematic review is to critically appraise and qualitatively synthesize the results of the availa…