OBJECTIVE: To estimate the total number of infants born globally between 1978 and 2018 after assisted reproductive technology (ART). Estimates are based on epidemiological data systematically and uniquely collected by the International Comm…
OBJECTIVE: To report the utilization, effectiveness, and safety of assisted reproductive technologies (ARTs) in 2019. DESIGN: A retrospective, cross-sectional survey derived from cycle and pregnancy outcome data submitted by national and r…
OBJECTIVE: To report utilization, effectiveness, and safety of assisted reproductive technologies in 2015 and 2016. DESIGN: A retrospective, cross-sectional survey of 3,103 assisted reproductive technology clinics in 74 countries in 2015 a…
STUDY QUESTION: Does cost-to-baby, expressed as a percentage of median household income (HHI), predict population-level utilization of ART across countries? SUMMARY ANSWER: ART affordability follows a power-law relationship with population…
BACKGROUND: Despite the availability of endometriosis care guidelines from multiple governmental and professional organisations, their global applicability and recommendations have been insufficiently examined. This scoping review examines …
INTRODUCTION: Global total fertility rates (TFR) are declining by approximately 1% annually due to factors such as increasing use of contraceptives, urbanisation, a shift in social norms, educational and socioeconomic changes among others. …
STUDY QUESTION: What updates of the International Glossary on Infertility and Fertility Care are required, to reflect contemporary scientific knowledge, social needs, and inclusive definitions, while harmonizing international communication …
Guidance on standards of care, particularly incorporating region-specific needs, is foundational to high-quality healthcare. The availability of region-specific guidance on endometriosis care has not been documented, especially in low- and …
BACKGROUND: Infertility is an underrecognized disease which affects over 17% of the reproductive age population worldwide. However, availability of, and access to, assisted reproductive technology (ART) is variable across countries. There a…
BACKGROUND: Family-planning policies have focused on contraceptive approaches to avoid unintended pregnancies, postpone, or terminate pregnancies and mitigate population growth. These policies have contributed to significantly slowing world…
STUDY QUESTION: What is the association between a country's level of gender equality and access to ART, as measured through ART utilization? SUMMARY ANSWER: ART utilization is associated with a country's level of gender equality even after…
OBJECTIVE: The World Endometriosis Research Foundation established the Endometriosis Phenome and Biobanking Harmonisation Project (EPHect) to create standardized documentation tools (with common data elements) to facilitate the comparison a…
OBJECTIVE: Review the safety of fertility preservation through ovarian stimulation with oocyte or embryo cryopreservation, including cycle and medication options. EVIDENCE REVIEW: A systematic review of peer-reviewed sources revealed 2 app…
STUDY QUESTION: Can the priorities for future research in infertility be identified? SUMMARY ANSWER: The top 10 research priorities for the four areas of male infertility, female and unexplained infertility, medically assisted reproduction…
STUDY QUESTION: Is electronic digital classification/staging of endometriosis by the EQUSUM application more accurate in calculating the scores/stages and is it easier to use compared to non-digital classification? SUMMARY ANSWER: We devel…
STUDY QUESTION: Can the priorities for future research in infertility be identified? SUMMARY ANSWER: The top 10 research priorities for the four areas of male infertility, female and unexplained infertility, medically assisted reproduction…
Challenges intrinsic to the accurate diagnosis of endometriosis contribute to an extended delay between the onset of symptoms and clinical confirmation. Intraoperative visualization, preferably with histologic verification, is considered by…
Background: Clinical management of endometriomas, prior to starting treatment with assisted reproductive technologies (ART), has since long been a matter of debate. Whereas cystectomy has been advocated in the past, recently more evidence h…
STUDY QUESTION: Can live birth be accurately predicted following surgical resection of moderate-severe (Stage III-IV) endometriosis? SUMMARY ANSWER: Live births can accurately be predicted with the endometriosis fertility index (EFI), with…