Wolfgang Schwede

No ORCID on file · 5 papers in corpus · active 2008-2018

Study types

  • other 2
  • article 1
  • paratext 1
  • review 1

Condition tags

  • endometriosis 4
  • infertility 1
article 2018
ChemMedChem ·doi:10.1002/cmdc.201800487

Progesterone plays an important role in the female reproductive system. However, there is also evidence that gynecologic disorders/diseases such as uterine fibroids and endometriosis are progesterone-dependent. Steroidal and non-steroidal s…

paratext 2018
·doi:10.1002/cmdc.201800681

The Front Cover shows vilaprisan, a highly selective progesterone receptor modulator (SPRM), bound to the progesterone receptor (PR). Gynecologic diseases such as uterine fibroids and endometriosis depend on progesterone receptor function. …

other 2013
Human Reproduction ·doi:10.1093/humrep/det247

STUDY QUESTION: Does the novel progesterone receptor (PR) modulator BAY 1002670, based on its preclinical pharmacological profile, offer a potential novel treatment option for uterine fibroids? SUMMARY ANSWER: The newly synthesized BAY1002…

other 2009
The Journal of steroid biochemistry and molecular biology ·doi:10.1016/j.jsbmb.2008.11.015

Progesterone receptor modulators (PRMs) play an important role in women's health. They are widely used in oral contraception or hormone therapy, and provide an attractive treatment approach for gynecological disorders such as uterine leiomy…

review 2008
Expert opinion on investigational drugs ·doi:10.1517/13543784.17.4.469

BACKGROUND: Clinical evidence has shown that conditions such as uterine fibroids, endometriosis and breast cancer are progesterone-dependent diseases. Therefore, progesterone receptor (PR) antagonists and selective PR modulators (SPRMs) are…