Chatterjea D

No ORCID on file · 4 papers in corpus · active 2012-2023
2023
Immune mechanisms in vulvodynia: key roles for mast cells and fibroblasts.
Frontiers in cellular and infection microbiology ·doi:10.3389/fcimb.2023.1215380

Vulvodynia is a debilitating condition characterized by painful sensitivity to touch and pressure in the vestibular tissue surrounding the vaginal opening. It is often a "diagnosis of exclusion" of idiopathic pain made in the absence of vis…

2019
Repeated Vaginal Exposures to the Common Cosmetic and Household Preservative Methylisothiazolinone Induce Persistent, Mast Cell-Dependent Genital Pain in ND4 Mice.
International journal of molecular sciences ·doi:10.3390/ijms20215361

A history of allergies doubles the risk of vulvodynia-a chronic pain condition of unknown etiology often accompanied by increases in numbers of vulvar mast cells. We previously established the biological plausibility of this relationship in…

2015
Mast cells: versatile gatekeepers of pain.
Molecular immunology ·doi:10.1016/j.molimm.2014.03.001

Mast cells are important first responders in protective pain responses that provoke withdrawal from intense, noxious environmental stimuli, in part because of their sentinel location in tissue-environment interfaces. In chronic pain disorde…

2012
Mast cell degranulation mediates compound 48/80-induced hyperalgesia in mice.
Biochemical and biophysical research communications ·doi:10.1016/j.bbrc.2012.07.074

Mast cells mediate allergies, hypersensitivities, host defense, and venom neutralization. An area of recent interest is the contribution of mast cells to inflammatory pain. Here we found that specific, local activation of mast cells produce…