Luan Y

No ORCID on file · 6 papers in corpus · active 2021-2026
2026
CDH4/UBA1/RBMX axis promotes polycystic ovary syndrome progression through YAP1 activation.
Cellular & molecular biology letters ·doi:10.1186/s11658-026-00900-4

BACKGROUND: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among women of childbearing age. In addition, it is a heterogeneous disease with numerous etiologies, multiple levels, and uneven manifestation. In patients …

2025
Fetal birthweight and maternal urinary incontinence in Chinese primiparas: a population-based study.
BMC public health ·doi:10.1186/s12889-025-21849-7

BackgroundUrinary incontinence (UI) is commonly linked to pregnancy and obstetric factors, but the association between fetal birthweight and maternal UI remains contentious. This study investigates the association between fetal birthweight …

2025
Prevalence of urinary incontinence among nulliparous women and its association with underweight body mass index: a secondary analysis of a nationwide cross-sectional study in China.
BMJ open ·doi:10.1136/bmjopen-2024-097807

ObjectivesTo estimate the prevalence of urinary incontinence (UI) and its subtypes among nulliparous Chinese women with associated risk factors. The prevalence of UI among those living in urban or rural communities was also analysed with po…

2025
Transcription factor ELF-1 protects against colitis by maintaining intestinal epithelium homeostasis.
Communications biology ·doi:10.1038/s42003-025-07742-4

Inflammatory bowel disease (IBD) is a chronic, relapsing, and remitting disease characterized by chronic inflammation in the gastrointestinal tract. The exact etiology and pathogenesis of IBD remain elusive. Although ELF-1 has been known to…

2022
Evidence of cancer therapy-induced chronic inflammation in the ovary across multiple species: A potential cause of persistent tissue damage and follicle depletion.
Journal of Reproductive Immunology ·doi:10.1016/j.jri.2022.103491

Chemotherapy and radiation treatments are known for deleterious effects on the ovary, which can result in prolonged recovery time before ovarian function resumes, including follicular growth after completion of these therapies. To better un…

2021
The Role of Mutant p63 in Female Fertility.
International journal of molecular sciences ·doi:10.3390/ijms22168968

The transcription factor p63, one of the p53 family members, plays an essential role in regulating maternal reproduction and genomic integrity as well as epidermal development. TP63 (human)/Trp63 (mouse) produces multiple isoforms: TAp63 an…