Konrad Stawiski

Hereditary breast and ovarian cancer syndrome (HBOC) is principally caused by germline mutations in BRCA1 and BRCA2. However, most women with HBOC are undiagnosed, and some patients meeting clinical criteria for HBOC will have no identifiab…

Abstract Background Lack of knowledge on the processes driving endometriosis hinders early detection and therapy development. Our purpose was to identify key molecular events involved in lesion formation across diverse populations and to de…

BACKGROUND: Molecular events that drive endometriosis (EM) and cause accompanying immune deregulation remain elusive. Our purpose was to identify key pathways involved in lesion formation across diverse populations and to detect transcripto…

The dataset containing the results of network meta-analysis comparing gene expression in three tissue types: EL - endometriosis lesion, EEM -eutopic endometrium from women with endometriosis, EH - eutopic endometrium from women without endo…

The dataset containing the results of network meta-analysis comparing gene expression in three tissue types: EL - endometriosis lesion, EEM -eutopic endometrium from women with endometriosis, EH - eutopic endometrium from women without endo…

INTRODUCTION: Prior studies have investigated the diagnostic potential of microRNA (miRNA) expression profiles for endometriosis. However, the vast majority of previous studies have only included adult women. Therefore, we sought to investi…

ObjectiveTo determine whether a multimodal assay combining serum microRNA with protein biomarkers and metadata improves triage assessment of an adnexal mass.MethodsSerum samples from 468 training subjects (191 cancer cases and 277 benign ad…

Recent studies posit a role for non-coding RNAs in epithelial ovarian cancer (EOC). Combining small RNA sequencing from 179 human serum samples with a neural network analysis produced a miRNA algorithm for diagnosis of EOC (AUC 0.90; 95% CI…