M W Laschke
No ORCID on file
· 9 papers in corpus
· active 2005-2014
Study types
- article 5
- other 2
- review 2
Condition tags
- endometriosis 9
- infertility 1
Top journals
Frequent coauthors
article
2014
STUDY QUESTION: Is telmisartan effective in the treatment of endometriosis? SUMMARY ANSWER: Combined blockade of angiotensin II type 1 receptor (AT1R) and activation of peroxisome proliferator-activated receptor (PPAR)-γ by telmisartan inhi…
other
2014
Endometriosis is one of the most frequent benign diseases in women of child-bearing age. The main symptoms are chronic upper abdominal pain and infertility. However, the aetiology and pathogenesis of endometriosis are as yet insufficiently …
article
2013
STUDY QUESTION: Does the phytochemical compound resveratrol inhibit vascularization of endometriotic lesions? SUMMARY ANSWER: Resveratrol suppresses the development of new microvessels in endometriotic lesions by inhibiting endothelial cell…
review
2012
BACKGROUND Angiogenesis, i.e. the development of new blood vessels from pre-existing ones, represents an integral part in the pathogenesis of endometriosis. During the last decade, an increasing number of studies have therefore focused on t…
other
2012
BACKGROUND: Xanthohumol is a prenylated flavonoid isolated from hops, which is known to act as a pleiotropic cancer chemopreventive agent owing to its anti-proliferative, anti-inflammatory and anti-angiogenic properties. In the present stud…
article
2011
BACKGROUND AND PURPOSE: 4-Hydroxybenzyl alcohol (HBA) is a phenolic plant compound, which has been shown to influence many cellular mechanisms. In the present study, we analysed in vitro and in vivo the anti-angiogenic actions of this pleio…
review
2011
BACKGROUND; Endometriosis is a complex disease with a multifactorial pathogenesis, which is crucially dependent on the development of new blood vessels. Based on the current literature, the present review highlights the fact that the neovas…
article
2006
BACKGROUND AND PURPOSE: Rapamycin is a widely used drug with antifungal, immunosuppressant and antiangiogenic effects. Herein, we studied whether immunosuppressive doses of rapamycin are capable of influencing endometriotic lesions. EXPERIM…
article
2005
BACKGROUND: Angiogenesis represents the crucial step in the pathogenesis of endometriosis, because endometriotic lesions require neovascularization to establish, proliferate and invade inside the peritoneal cavity. To elucidate the role of …