Caroline B. Appleyard

ORCID: 0000-0002-1211-4246 · 59 papers in corpus
lab-animal 2012
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719112438443

Women with endometriosis have significant emotional distress; however, the contribution of stress to the pathophysiology of this disease is unclear. We used a rat model of endometriosis to examine the effects of stress on the development of…

2011
lab-animal 2009
·doi:10.1096/fasebj.23.1_supplement.980.6

The contribution of stress to the symptoms and progression of endometriosis, a chronic disease characterized by pain, peritoneal inflammation, adhesions and cysts, is unclear. AIM Examine the effect of stress on the expression of S‐100 (a m…

lab-animal 2008
·doi:10.1096/fasebj.22.1_supplement.1189.1

It is not known whether stress affects the severity of endometriosis in women. Aim: Assess the effects of chronic stress in an established animal model of intestinal endometriosis. Methods: Endometriosis was surgically induced in female rat…

lab-animal 2007
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719107309722

Endometriosis commonly presents with symptoms that mimic chronic gastrointestinal disorders. The authors used the autotransplantion model of endometriosis in rats to investigate the possible underlying mechanisms. After the rats were killed…

lab-animal 2007
Fertility and sterility ·doi:10.1016/j.fertnstert.2006.07.1550

OBJECTIVE: To validate a rat model of endometriosis using complimentary DNA (cDNA) microarrays by identifying common gene expression patterns between experimental and natural disease. DESIGN: Autotransplantation rat model. SETTING: Medica…

2006
lab-animal 2005
Biology of reproduction ·doi:10.1095/biolreprod.105.044131

Endometriosis is commonly associated with symptoms similar to those of gastrointestinal diseases, such as inflammatory bowel disease (IBD), leading to erroneous diagnosis and inappropriate management. The role of tumor necrosis factor alpha…

2002