D'Hooghe T

No ORCID on file · 123 papers in corpus · active 1994-2026

Study types

  • article 37
  • other 33
  • review 26
  • letter 3
  • erratum 2

Condition tags

  • endometriosis 85
  • infertility 24
  • dysmenorrhea 7
  • chronic_pelvic_pain 7
  • adenomyosis 4
  • bowel_endometriosis 3
  • die_deep_infiltrating 3
  • dyspareunia 3
  • disambig:endometritis 1
  • mesh:D004716 1
other 2026
Fertility and sterility ·doi:10.1016/j.fertnstert.2026.03.020

OBJECTIVE: To examine intrapatient variability in retrieved oocyte numbers across consecutive in vitro fertilization (IVF) ovarian stimulation (OS) cycles with an identical OS protocol. DESIGN: Cross-continental, multicenter retrospective …

other 2026
Fertility and sterility ·doi:10.1016/j.fertnstert.2025.12.010
other 2025
Gynecologic and obstetric investigation ·doi:10.1159/000542074

OBJECTIVE: Various gonadotropins are used for ovarian stimulation (OS). This study investigated the cost-effectiveness of different gonadotropins based on real-world data from the French National Health Database (SNDS) over a 7-year follow-…

review 2025
Fertility and sterility ·doi:10.1016/j.fertnstert.2025.06.026

OBJECTIVE: To address the reporting of minimal clinically important differences (MCIDs) in the published literature and investigate the utility of absolute and relative differences when defining this parameter. DESIGN: Expert opinion. SUB…

other 2025
Fertility and sterility ·doi:10.1016/j.fertnstert.2024.10.001

OBJECTIVE: To assess the adequate ovarian follicular development and oocyte recovery between ovarian potential (antral follicle count [AFC]) before the start of ovarian stimulation (OS) and oocyte quantity and quality at oocyte retrieval. A…

2025
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-025-01480-2

BackgroundMorphological embryo assessment, time-lapse imaging or PGT-A can prioritize an embryo for transfer in IVF/ICSI cycles. Nevertheless, there remains potential to enhance the efficiency of ART cycles and reduce the time-to-pregnancy.…

other 2025
Fertility and sterility ·doi:10.1016/j.fertnstert.2025.05.168

OBJECTIVE: To provide a framework for conducting rigorous nonrandomized studies of interventions in fertility treatment research, addressing their role as complements to randomized controlled trials (RCTs) in evaluating treatment outcomes. …

other 2024
International journal of molecular sciences ·doi:10.3390/ijms25179405

Highly purified human menopausal gonadotropin (HP-hMG [Menopur®, Ferring Pharmaceuticals, Saint-Prex, Switzerland]) contains a 1:1 ratio of follicle-stimulating hormone (FSH) and luteinizing hormone (LH). This analysis aimed to assess gonad…

other 2024
Expert opinion on drug delivery ·doi:10.1080/17425247.2024.2311127

BACKGROUND: This study aimed to confirm that the incremental dose/clicks system dispenses accurate doses for the Merck family of fertility pen injectors. RESEARCH DESIGN AND METHODS: Set doses (Vset) for three dose dial settings (minimum d…

other 2024
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2023.103725

RESEARCH QUESTION: According to real-world data, is recombinant human FSH (r-hFSH) combined with recombinant human LH (r-hLH) or r-hFSH alone more effective for women of advanced maternal age (AMA) in terms of live birth? DESIGN: Non-inter…

other 2024
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-024-01291-x

BACKGROUND: Currently, there is no consensus on the optimal management of women with low prognosis in ART. In this Delphi consensus, a panel of international experts provided real-world clinical perspectives on a series of literature-suppor…

other 2023
International journal of molecular sciences ·doi:10.3390/ijms24098040

Various preparations of follicle-stimulating hormone (FSH) are commercially available; however, they differ in glycoforms composition and purity owing to their respective sources. Additional chemical/physical changes can also be introduced …

other 2023
Best practice & research. Clinical obstetrics & gynaecology ·doi:10.1016/j.bpobgyn.2022.102308

This comparative non-interventional study using data from the French National Health Database (Système National des Données de Santé) investigated real-world (cumulative) live birth outcomes following ovarian stimulation, leading to oocyte …

review 2023
Best practice & research. Clinical obstetrics & gynaecology ·doi:10.1016/j.bpobgyn.2023.102350

This non-interventional study compared the effectiveness of recombinant human follicle-stimulating hormone (r-hFSH) and recombinant human luteinizing hormone (r-hLH) (2:1 ratio) versus r-hFSH alone for ovarian stimulation (OS) during assist…

review 2023
Best practice & research. Clinical obstetrics & gynaecology ·doi:10.1016/j.bpobgyn.2023.102349

Considerable costs are associated with infertility treatment, but little evidence is available on the main drivers of treatment costs. This cost analysis investigated key costs for treatment with assisted reproductive technology (ART) and t…

2023
Frontiers in endocrinology ·doi:10.3389/fendo.2023.1195632

IntroductionFine-tuning of injectable gonadotropin doses during ovulation induction (OI) or ovarian stimulation (OS) treatment cycles with the aim of using doses low enough to minimize the risk of excessive ovarian response while maintainin…

review 2023
International journal of molecular sciences ·doi:10.3390/ijms24109020

Follicle-stimulating hormone (FSH), together with luteinizing hormone (LH) and human chorionic gonadotropin (hCG), plays a fundamental role in human reproduction. The discovery of FSH and other gonadotropins was a defining moment in our und…

2023
Genes ·doi:10.3390/genes14061269

BackgroundSpecific polymorphisms might influence controlled ovarian stimulation in women undergoing assisted reproductive technologies (ARTs). Data regarding possible interactions of these polymorphisms are still scanty. The aim of this ana…

other 2023
Journal of gynecology obstetrics and human reproduction ·doi:10.1016/j.jogoh.2023.102640
meta-analysis 2023
Nature genetics ·doi:10.1038/s41588-023-01323-z

Endometriosis is a common condition associated with debilitating pelvic pain and infertility. A genome-wide association study meta-analysis, including 60,674 cases and 701,926 controls of European and East Asian descent, identified 42 genom…

other 2023
Gynecologic and obstetric investigation ·doi:10.1159/000529304

OBJECTIVES: The objective of this study was to examine the prevalence of chronic endometritis (CE) in infertile women, its impact on reproductive outcomes, and the accuracy of hysteroscopy as a screening tool for CE. DESIGN: This was a pro…

2023
Clinical epigenetics ·doi:10.1186/s13148-023-01490-0

The constant decline in fertility and older reproductive age is the major cause of low clinical pregnancy rates in industrialised countries. Epigenetic mechanisms impact on proper embryonic development in women undergoing in vitro fertilisa…

other 2023
Best practice & research. Clinical obstetrics & gynaecology ·doi:10.1016/j.bpobgyn.2023.102340

Willingness to pay (WTP) for an infertility treatment is the maximum amount of money a patient is willing to pay per treatment, or to achieve a live birth or pregnancy. Such thresholds are important to determine the cost effectiveness of a …

review 2023
Best practice & research. Clinical obstetrics & gynaecology ·doi:10.1016/j.bpobgyn.2022.102301

A high ovarian response to conventional ovarian stimulation (OS) is characterized by an increased number of follicles and/or oocytes compared with a normal response (10-15 oocytes retrieved). According to current definitions, a high respons…

other 2022
International journal of molecular sciences ·doi:10.3390/ijms23126762

Although the full primary structures of the alfa and beta subunits of reference r-hFSH-alfa and its biosimilars are identical, cell context-dependent differences in the expressing cell lines and manufacturing process can lead to variations …