Bulmer JN

No ORCID on file · 8 papers in corpus · active 1995-2021

Study types

  • article 6
  • review 1

Condition tags

  • endometriosis 6
  • adenomyosis 3
article 2021
Transforming Growth Factor (TGF) β and Endometrial Vascular Maturation
Frontiers in cell and developmental biology ·doi:10.3389/fcell.2021.640065

Appropriate growth and development of the endometrium across the menstrual cycle is key for a woman’s quality of life and reproductive well-being. Recurrent pregnancy loss (RPL) and heavy menstrual bleeding (HMB) affect a significant propor…

2016
Pathophysiology of heavy menstrual bleeding.
Women's health (London, England) ·doi:10.2217/whe.15.81

Heavy menstrual bleeding (HMB) is a common gynecological complaint with multiple etiologies and diverse pathophysiological origins. This review discusses HMB with reference to the recently proposed PALM-COEIN classification system for abnor…

article 1998
Apoptosis and bcl-2 expression in normal human endometrium, endometriosis and adenomyosis
Human Reproduction ·doi:10.1093/humrep/13.12.3496

Apoptosis has been implicated in the pathogenesis of several diseases and is partly regulated by bcl-2, which blocks the apoptotic pathway and promotes cell survival. Apoptosis and bcl-2 expression were examined in paired eutopic and ectopi…

article 1998
Intraepithelial leukocytes in endometriosis and adenomyosis: comparison of eutopic and ectopic endometrium with normal endometrium
Human Reproduction ·doi:10.1093/humrep/13.10.2910

Intraepithelial leukocytes (IEL) are recognized as an important component of most mucosal surfaces but have received scant attention in the human female reproductive tract. The aim of the present study was to characterize, quantify and comp…

review 1998
Phenotypic and functional studies of leukocytes in human endometrium and endometriosis
Human reproduction update ·doi:10.1093/humupd/4.5.702

The aetiology of endometriosis, a common and disabling disorder, is presently unknown, although immune dysfunction could allow ectopic endometrial fragments to survive outside the uterine cavity. These studies investigate the relationship b…

article 1996
Immunohistochemical characterization of stromal leukocytes in ovarian endometriosis: comparison of eutopic and ectopic endometrium with normal endometrium
Fertility and Sterility ·doi:10.1016/s0015-0282(16)58391-5

ObjectiveTo compare stromal leukocyte subpopulations in different phases of the menstrual cycle in eutopic and ectopic endometrium from women with ovarian endometriosis and in control endometrium.DesignRetrospective immunohistochemical stud…

article 1995
Endometrial leukocyte subpopulations in women with endometriosis
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/0301-2115(95)02222-s

The aim of this study was to investigate whether the endometrium of women with endometriosis differs immunologically from the endometrium of normal fertile women. Endometrial biopsies were obtained from 18 normal fertile women who were requ…

article 1995
Immunohistochemical characterization of proliferation, oestrogen receptor and progesterone receptor expression in endometriosis: comparison of eutopic and ectopic endometrium with normal cycling endometrium
Human Reproduction ·doi:10.1093/oxfordjournals.humrep.a135901

Recent studies examining oestrogen and progesterone receptor status and the proliferative activity of endometriotic lesions have produced conflicting reports. This study aimed to clarify the receptor status and proliferative activity of eut…