Massimo Candiani

No ORCID on file · 157 papers in corpus · active 1991-2026

Study types

  • article 101
  • review 30
  • other 16
  • letter 4
  • meta-analysis 3

Condition tags

  • endometriosis 137
  • endometrioma 24
  • infertility 24
  • chronic_pelvic_pain 12
  • adenomyosis 8
  • dysmenorrhea 8
  • dyspareunia 6
  • bowel_endometriosis 5
  • die_deep_infiltrating 5
  • bladder_endometriosis 3
review 2014
Endometriosis‐associated tumor at the inguinal site: Report of a case diagnosed during pregnancy and literature review
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.12310

Malignant degeneration of endometriosis in the inguinal region is rare, and has only been reported in six cases in the literature, none of which was detected during pregnancy. We present the first case of endometriosis-associated adenocarci…

article 2014
Impact on ovarian reserve of second laparoscopic surgery for recurrent unilateral endometriotic cyst: case-control study
article 2014
Iron availability is increased in individual human ovarian follicles in close proximity to an endometrioma compared with distal ones
Human Reproduction ·doi:10.1093/humrep/det466

STUDY QUESTION: Does the iron content of an endometrioma represent a potential source of toxicity for the adjacent follicles? SUMMARY ANSWER: The presence of an endometrioma increases iron and H/L ferritin levels, and transferrin receptor (…

article 2014
Leisure and occupational physical activity at different ages and risk of endometriosis
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2014.10.031
article 2014
Microablative fractional CO2 laser improves sexuality in women with vulvovaginal atrophy.
review 2014
The Endometriotic Tissue Lining the Internal Surface of Endometrioma: Hormonal, Genetic, Epigenetic Status, and Gene Expression Profile
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719114529374
article 2014
The WNT/β-catenin signaling pathway and expression of survival promoting genes in luteinized granulosa cells: endometriosis as a paradigm for a dysregulated apoptosis pathway
Fertility and sterility ·doi:10.1016/j.fertnstert.2014.02.040
review 2014
Triptorelin for the treatment of endometriosis
Expert opinion on pharmacotherapy ·doi:10.1517/14656566.2014.916279

INTRODUCTION: Over the past 30 years, gonadotropin-releasing hormone agonists (GnRH-a) have been used to induce a hypoestrogenic status in women with endometriosis with the aim to cause an improvement in pain symptoms similar to that observ…

review 2013
Diet and endometriosis risk: A literature review
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2012.12.011
article 2013
Unravelling the Ovarian Endometrioma Pathogenesis: “The Long and Winding Road” across the Various Theories
·doi:10.5301/je.5000156

Controversy exists regarding the pathogenesis of endometriotic ovarian cysts. Different and complex theories have been proposed over the years since the description of chocolate cysts by Sampson in 1921. We have herein reviewed findings in …

review 2012
An Italian association study and meta-analysis with previous GWAS confirm WNT4, CDKN2BAS and FN1 as the first identified susceptibility loci for endometriosis
Journal of medical genetics ·doi:10.1136/jmedgenet-2012-101257

BACKGROUND: Although endometriosis may benefit from primary prevention measures, the epidemiological risk factors identified are equivocal. Two genome-wide association studies (GWAS) have been conducted for endometriosis in two different et…

letter 2012
An ovarian endometriotic cyst in a patient with prepubertal hypopituitarism due to a craniopharyngioma: a clue for endometrioma pathogenesis
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2012.05.016
article 2012
Continuous low‐dose oral contraceptive in the treatment of colorectal endometriosis evaluated by rectal endoscopic ultrasonography
Acta obstetricia et gynecologica Scandinavica ·doi:10.1111/j.1600-0412.2012.01366.x

OBJECTIVE: Limited attention has been focused on the medical treatment of bowel endometriosis. This study evaluates the efficacy of administration of a continuous low-dose oral contraceptive in treating pain and other symptoms associated wi…

review 2012
Principles of phenomics in endometriosis
Human reproduction update ·doi:10.1093/humupd/dms001

BACKGROUND: Endometriosis has been associated with specific morphometric characteristics and pigmentary traits. The purpose of this study was to systematically review prior publications dealing with this aspect in order to revisit phenotypi…

article 2012
Progesterone Resistance, Aromatase, and Inflammation: The Important Relationships Between Hormones and Inflammation
·doi:10.1007/s13669-012-0013-8
review 2012
The molecular connections between the cannabinoid system and endometriosis
Molecular human reproduction ·doi:10.1093/molehr/gas037

The endocannabinoid system consists of an array of endogenously produced bioactive lipids that activate cannabinoid 1 (CB1) and 2 (CB2) receptors. Alterations of this system have been described in almost every category of disease. These cha…

article 2012
The selective vitamin D receptor agonist, elocalcitol, reduces endometriosis development in a mouse model by inhibiting peritoneal inflammation
Human Reproduction ·doi:10.1093/humrep/des150

BACKGROUND: Endometriosis, which is characterized by the growth of endometrial tissue at ectopic locations as well as vascular development and inflammation, is still an unmet clinical need since an optimal drug that allows for both pain and…

article 2012
Unraveling the two entities of endometrioid ovarian cancer: A single center clinical experience
Gynecologic oncology ·doi:10.1016/j.ygyno.2012.05.007
article 2011
Deep pelvic endometriosis negatively affects ovarian reserve and the number of oocytes retrieved for in vitro fertilization
Acta obstetricia et gynecologica Scandinavica ·doi:10.1111/j.1600-0412.2011.01161.x

OBJECTIVE: Endometriosis-associated infertility results in reduced ovarian response, fewer oocytes available for fertilization, compromised oocyte quality and higher miscarriage rates. A consistent proportion of women with endometriosis req…

other 2011
High rate of endometriosis recurrence in young women
Journal of pediatric and adolescent gynecology ·doi:10.1016/j.jpag.2011.06.012

OBJECTIVE: To evaluate rate and determinants of long-term recurrence of endometriosis in a population of young women. DESIGN: Retrospective cohort study. SETTING: University tertiary care referral center for women with benign gynecologic …

review 2011
Surgical measures for endometriosis-related infertility: A plea for research
Placenta ·doi:10.1016/j.placenta.2011.06.011
article 2011
The concomitant presence of deep infiltrating endometriosis worsens the endometrioma-related negative impact on ovarian reserve and the number of retrieved oocytes
·doi:10.1016/j.placenta.2011.07.020
article 2010
Endoscopic rectal ultrasound and elastosonography are useful in flow chart for the diagnosis of deep pelvic endometriosis with rectal involvement
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/j.1447-0756.2010.01413.x

Abstract Aim: Endometriosis is defined by the presence of endometrial glands and stroma outside the uterus. The disease causes pelvic pain, dysmenorrhea, dyspareunia, dyschezia and urinary symptoms. The aim of this study was to assess the u…

article 2010
Peculiar aspects of endometriosis in adolescents
·doi:10.5301/je.2010.595

Although documented rates of endometriosis in adolescent patients undergoing laparoscopy for chronic pelvic pain range from about 25% to 45%, adolescent endometriosis has received limited attention in terms of research activity and follow-u…

article 2010
Peculiar Aspects of Endometriosis in Adolescents
·doi:10.1177/228402651000200104

Although documented rates of endometriosis in adolescent patients undergoing laparoscopy for chronic pelvic pain range from about 25% to 45%, adolescent endometriosis has received limited attention in terms of research activity and follow-u…