Wonhyoung Park

No ORCID on file · 10 papers in corpus · active 2020-2025

Study types

  • article 8
  • other 1
  • review 1

Condition tags

  • endometriosis 10
  • infertility 4
article 2025
Carvacrol Shows Potential as a Treatment for Endometriosis with Inflammatory Reaction and Antioxidant Properties, Demonstrated in both In Vivo and In Vitro Studies
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-025-01866-y

Carvacrol is a phenolic monoterpenoid found in essential oils of oregano, thyme, and other plants. It possesses pharmacological activities, including antioxidant, anticancer, and anti-inflammatory properties, against several diseases. Howev…

article 2025
Endometriosis lesion growth inhibition and immune modulation function of thymol in vitro and in vivo
Toxicology and applied pharmacology ·doi:10.1016/j.taap.2025.117648

Thymol, a phenolic monoterpene derivative found in the essential oil of Thymus vulgaris L., Lamiaceae, is currently under investigation for potential applications in pharmaceuticals, functional foods, and cosmetics. Despite ongoing research…

review 2025
Female reproductive disease, endometriosis: From inflammation to infertility
Molecules and cells ·doi:10.1016/j.mocell.2024.100164

Despite the fact that endometriosis is a common gynecological disease that occurs in 10% of women of reproductive age, the pathogenesis and treatment strategy are not clear to date. Endometriosis patients are commonly characterized by adhes…

article 2024
Alteration in Effects of Endometriosis on Fecundity According to Pregnancy Experience in Mouse Model
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-023-01426-2

This study is aimed at identifying variations in the effect of endometriosis on fecundity in a mouse model based on prior pregnancy experience. Endometriosis is one of the most prevalent gynecological diseases and is known to impact female …

article 2024
Dimethyl Fumarate Ameliorates the Endometriosis Through Anti‐Inflammatory and Anti‐Proliferation Mechanisms In Vitro and In Vivo
·doi:10.1002/adtp.202400237

Abstract Dimethyl fumarate is a widely known therapeutic agent with anti‐inflammatory properties for psoriasis and multiple sclerosis. Despite the current attempts to use dimethyl fumarate for treating various inflammatory diseases, its eff…

article 2024
Therapeutic effects of S-allyl-L-cysteine in a mouse endometriosis model and its immunomodulatory effects via regulation of T cell subsets and cytokine expression
Pharmacological reports : PR ·doi:10.1007/s43440-024-00625-1

BACKGROUND: Endometriosis is a female hormone-dependent gynecological disorder characterized by chronic inflammation. Therefore, the development of novel treatment strategies that can diminish the side effects of the long-term use of hormon…

other 2024
Therapeutic efficacy and anti-inflammatory mechanism of baicalein on endometriosis progression in patient-derived cell line and mouse model
Phytomedicine : international journal of phytotherapy and phytopharmacology ·doi:10.1016/j.phymed.2024.155469

BACKGROUND: Baicalein is a flavonoid extracted from the roots of Scutellaria baicalensis G. that has anti-inflammatory and antitumor effects. However, therapeutic mechanisms of baicalein in patients with endometriosis in vivo have yet to be…

article 2023
Fraxetin reduces endometriotic lesions through activation of ER stress, induction of mitochondria-mediated apoptosis, and generation of ROS
Phytomedicine : international journal of phytotherapy and phytopharmacology ·doi:10.1016/j.phymed.2023.155187

BACKGROUND: Fraxetin, a phytochemical obtained from Fraxinus rhynchophylla, is well known for its anti-inflammatory and anti-fibrotic properties. However, fraxetin regulates the progression of endometriosis, which is a benign reproductive d…

article 2022
Melatonin inhibits endometriosis development by disrupting mitochondrial function and regulating tiRNAs
Journal of pineal research ·doi:10.1111/jpi.12842

Endometriosis is a benign gynecological disease characterized by abnormal growth of endometrial-like cells outside the uterus. Melatonin, a hormone secreted by the pineal gland, has been shown to have therapeutic effects in various diseases…

article 2020
5,7‐Dimethoxyflavone induces apoptotic cell death in human endometriosis cell lines by activating the endoplasmic reticulum stress pathway
Phytotherapy research : PTR ·doi:10.1002/ptr.6677

Endometriosis is a reproductive disorder characterized by the dislocation of endometrial tissues. Approximately 5-20% of women at their reproductive age are diagnosed with endometriosis, which causes chronic pain and infertility. Here, we d…