Cao Y

Adenomyosis is characterized by the invasion of endometrial glands and stroma into the myometrium. Its clinical manifestations often include dysmenorrhoea, excessive menstrual bleeding and infertility. Reduced pregnancy and live birth rates…

PURPOSE: Bladder cancer is one of the ten most common cancers in the world, with a high incidence rate and mortality, and therefore a major burden on the global health care system. PID1 (Phosphotyrosine Interaction Domain 1) functions as an…

BACKGROUND: Threatened abortion is a common obstetric complication where early risk stratification is crucial for clinical management. CA125, a glycoprotein biomarker produced by endometrial and trophoblastic tissues, may serve as a valuabl…

OBJECTIVES: This meta-analysis seeks to clarify the relationship between hysterectomy, oophorectomy, and the subsequent risk of developing breast cancer. METHODS: A comprehensive literature search was conducted across PubMed, the Cochrane …

Traumatic brain injury (TBI) is a recognized global public health problem. However, there are still limitations in the available therapeutic approaches and a lack of clinically effective drugs. Therefore, an in-depth exploration of the seco…

BACKGROUND: Preimplantation embryos in vivo are exposed to various growth factors in the female reproductive tract that are absent in in vitro embryo culture media. Cell-free fat extract exerts antioxidant, anti-ageing, and ovarian function…

RATIONALE: Benign gynecological disorders causing abnormal uterine bleeding (AUB), such as adenomyosis, may trigger recurrent thrombosis similar to Trousseau syndrome. Trousseau syndrome is characterized by recurrent thrombotic events in pa…

BACKGROUND: Limited information is available on malpractice claims against obstetricians and gynecologists in China. This study identifies risk factors associated with malpractice and explores the correlation between the hospital characteri…

INTRODUCTION: Recurrent spontaneous abortion (RSA) demonstrates a complex pathogenesis. The uterine artery (UtA) Doppler ultrasound monitoring is clinically valuable for predicting RSA risk. OBJECTIVE: This study aimed to assess the type o…

ABSTRACT: In order to determine the number of eggs to be retrieved to maximize live birth outcomes, this study aimed to develop a clinical prediction model that would identify important predictors of cumulative live birth rate after intracy…

OBJECTIVE: To explore the single and combined therapeutic effects of warm silver needle acupuncture and myofascial trigger point (MTrP) intervention on chronic pelvic pain (CPP). METHODS: CPP patients underwent treatment with warm silver n…

Endometriosis (EMs) is a chronic gynecologic condition characterized by the growth of endometrial stromal and glandular tissue outside the uterine cavity of unknown etiology. Currently, ferroptosis resistance, increased glycolysis, and incr…

As a complex chronic gynecological disorder characterized by multifaceted etiology involving genetics, environment, immunity and inflammation, endometriosis (EM) has long been a significant concern for women of reproductive age worldwide. T…

BACKGROUND: Acute pancreatitis (AP) is an inflammatory disease of the pancreas marked by inflammation and acinar cell necrosis. Scutellariae Barbata (S. Barbata), a traditional Chinese herb for inflammation, has unclear efficacy for AP. PU…

Adenomyosis, characterized by clinical intractability, significantly impacts female fertility and life quality due to the absence of definitive diagnostic markers and effective treatment options. The invagination theory is a primary hypothe…

BACKGROUND: Endometriosis is a chronic inflammatory gynecological disease. Previous studies have explored relationships between endometriosis and the microbiota, but none have focused on differences in gut microbiota between early-stage and…

Endometriosis (EMs) is a chronic, estrogen-dependent disease defined by the presence of endometrial-like tissue outside the uterine cavity. Gut microbiota has emerged as potent inducer for chronic inflammatory disease, yet whether its mecha…

Background: Endometriosis (EM) is a prevalent and complex disease affecting women of reproductive age, with significant individual and societal burdens. Despite extensive research, the underlying etiology of EM remains poorly understood. Pr…

STUDY QUESTION: Can harmine mitigate endometriosis by modulating oxidative phosphorylation (OXPHOS) suppression and macrophage polarization? SUMMARY ANSWER: Harmine induces apoptosis in endometriotic lesions by inhibiting OXPHOS while also…

PURPOSE: For unexpected low-prognosis patients (Group 1 and Group 2) defined by POSEIDON criteria, how to maximize the live birth rate while controlling the multiple birth rate by tailoring the embryo transfer number and quality? METHODS: …

BACKGROUND: Ferroptosis and cuproptosis are closely associated with hepatic ischemia-reperfusion injury (HIRI). However, the significance of metabolic cell death-related genes (MRGs) in HIRI still awaits exploration. This study examined the…

Abstract Delayed diagnosis of endometriosis (EM) can significantly hinder treatment options and patient prognosis, adversely affecting fertility and increasing the risk of malignancy. Current diagnostic methods are invasive. In our study, …

Postpartum uterine necrosis is a rare and serious complication. The uterine tissue becomes devascularized and then causes endometrial necrosis and even myometrial necrosis, usually combing with uterine infection. To clear the infection, hys…

OBJECTIVE: Proteomic analysis was conducted on human follicular fluid (FF) using the 4D label-free method to identify proteins potentially influencing oocyte quality in hyperandrogenic (HA) polycystic ovary syndrome (PCOS) patients. METHOD…