Coskun S

No ORCID on file · 6 papers in corpus · active 1998-2026
2026
Pathogenic homozygous PLCZ1 mutation reduces sperm protein levels with a simulated reduction of PIP2 binding: a case report.
Reproduction & fertility ·doi:10.1530/raf-25-0085

AbstractMammalian oocyte activation is driven by intracellular calcium (Ca2+) oscillations induced by sperm-specific phospholipase C zeta (PLCζ). Sperm PLCζ deficiency is linked to male infertility caused by oocyte activation deficiency. Us…

2022
Global Transcriptional Profiling of Granulosa Cells from Polycystic Ovary Syndrome Patients: Comparative Analyses of Patients with or without History of Ovarian Hyperstimulation Syndrome Reveals Distinct Biomarkers and Pathways.
Journal of clinical medicine ·doi:10.3390/jcm11236941

Ovarian hyperstimulation syndrome (OHSS) is often a complication of polycystic ovarian syndrome (PCOS), the most frequent disorder of the endocrine system, which affects women in their reproductive years. The etiology of OHSS is multifactor…

2021
Oxidative stress and DNA damage status in couples undergoing in vitro fertilization treatment.
Reproduction & fertility ·doi:10.1530/raf-20-0062

This study examined the status of oxidative stress in 599 couples undertaking in vitro fertilization (IVF) treatment and its association with reproductive hormones, smoking, and outcomes. Oxidative stress biomarkers such as malondialdehyde,…

2017
Intramuscular progesterone (Gestone) versus vaginal progesterone suppository (Cyclogest) for luteal phase support in cycles of in vitro fertilization-embryo transfer: patient preference and drug efficacy.
Fertility research and practice ·doi:10.1186/s40738-017-0044-y

BackgroundThe requirement for luteal phase support (LPS) in stimulated IVF cycles is well established, however drug choice, and route of administration and duration of use are not. This report evaluates patients' preference and satisfaction…

2016
Association of blood groups with ovarian reserve and outcome of in vitro fertilization treatment.
Annals of Saudi medicine ·doi:10.5144/0256-4947.2016.31.3.1700

BackgroundThe association between ABO blood groups and ovarian reserve in infertile patients has been a point of controversy.ObjectivesThe aim of this study was to assess the correlation of certain blood groups with ovarian reserve and resp…

1998
Effects of reducing insemination time in human in vitro fertilization and embryo development by using sibling oocytes.
Journal of assisted reproduction and genetics ·doi:10.1023/a:1020333427698

PurposeRecent studies showed a beneficial effect of reducing the time of sperm-oocyte interaction on fertilization, division, and implantation rates of the oocytes obtained from randomized patients. In the present study, the effects of redu…