Huang JH

No ORCID on file · 7 papers in corpus · active 2018-2021

Study types

  • article 5
  • other 1

Condition tags

  • adenomyosis 6
  • dysmenorrhea 1
other 2021
Elevated Circular RNA PVT1 Promotes Eutopic Endometrial Cell Proliferation and Invasion of Adenomyosis via miR-145/Talin1 Axis
BioMed research international ·doi:10.1155/2021/8868700

Several theories on the origin of adenomyosis (ADS) have been proposed, of which the most widely accepted is the fundamental pathogenic role of uterine eutopic endometrium. Emerging evidence suggests that circular RNAs participate in the mu…

article 2021
Estrogen 17β‑estradiol accelerates the proliferation of uterine junctional zone smooth muscle cells via the let‑7a/Lin28B axis in adenomyosis
Molecular medicine reports ·doi:10.3892/mmr.2021.11976

The estrogen 17β‑estradiol has been proven to serve an indispensable role in the occurrence and development of adenomyosis (ADS). The let‑7a/Lin28B axis can control cell proliferation by acting as a tumor‑inhibiting axis in numerous types o…

article 2021
Talin1 Induces Epithelial-Mesenchymal Transition to Facilitate Endometrial Cell Migration and Invasion in Adenomyosis Under the Regulation of microRNA-145-5p
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-020-00444-8

Adenomyosis (ADS) is a commonly encountered benign gynecological disorder. Epithelial-mesenchymal transition (EMT) may serve a pivotal role in the pathogenesis of ADS. Talin1 has been identified to be implicated in multiple human carcinomas…

article 2021
Upregulated microRNA let-7a accelerates apoptosis and inhibits proliferation in uterine junctional zone smooth muscle cells in adenomyosis under conditions of a normal activated hippo-YAP1 axis
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-021-00753-w

BACKGROUND: Let-7a is a small non-coding RNA that has been found to take part in cell proliferation and apoptosis. The hippo-YAP1 axis, known as a tumour suppressor pathway, also plays an important role in cell proliferation and apoptosis. …

article 2021
Upregulated Talin1 synergistically boosts β-estradiol-induced proliferation and pro-angiogenesis of eutopic and ectopic endometrial stromal cells in adenomyosis
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-021-00756-7

Abstract Adenomyosis (ADS) is an estrogen-dependent gynecological disease with unspecified etiopathogenesis. Local hyperestrogenism may serve a key role in contributing to the origin of ADS. Talin1 is mostly identified to be overexpressed a…

article 2020
[Expression and significance of chemokine CXCL12 and receptor CXCR4 in adenomyosis].
Zhonghua fu chan ke za zhi ·doi:10.3760/cma.j.cn112141-20200226-00140

The levels of CXCL12 and CXCR4 in the endometrium and myometrium of adenomyosis are increased and positively correlated. The two chemokine may be involved in the development of adenomyosis.

2018
TTC39B rs1407977 SNP is associated with the risk of coronary heart disease and ischemic stroke.
International journal of clinical and experimental pathology

Previous genome-wide association studies have showed that several tetratricopeptide repeat domain protein 39B gene (TTC39B) single nucleotide polymorphisms (rs581080 and rs471364) were associated with serum high-density lipoprotein choleste…