[Expression and significance of chemokine CXCL12 and receptor CXCR4 in adenomyosis].

S Wang, Wang S, Shuo Wang, H Duan, Hua Duan, Duan H, Li BH, Bo Li, B H Li, Wang YY, Y Y Wang, Junhua Huang, Huang JH, J H Huang, Guo ZC, Z C Guo, Zhengchen Guo
Zhonghua fu chan ke za zhi · 2020 · vol. 55(11) , pp. 754–759 · doi:10.3760/cma.j.cn112141-20200226-00140 · PMID:33228346 · W3109159438
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-07 ⓘ

The study found increased levels of CXCL12 and CXCR4 in the endometrium and myometrium of adenomyosis patients, suggesting their involvement in the condition's development.

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Abstract

The levels of CXCL12 and CXCR4 in the endometrium and myometrium of adenomyosis are increased and positively correlated. The two chemokine may be involved in the development of adenomyosis.

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Condition tags

adenomyosis

MeSH descriptors

Adenomyosis Chemokine CXCL12 Endometrium Myometrium Receptors, CXCR4 Adenomyosis Adenomyosis Adenomyosis Biomarkers, Tumor Biomarkers, Tumor Chemokine CXCL12 Endometrium Endometrium Female Gene Expression Regulation, Neoplastic Humans Hysterectomy Myometrium Myometrium Pregnancy

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europepmc
last seen: 2026-09-06T09:34:12.023084+00:00
openalex
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pubmed
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License: CC0 · commercial use OK