Junhua Huang

ORCID: 0000-0001-8279-8674 · 6 papers in corpus
other 2021
Estrogen 17β‑estradiol accelerates the proliferation of uterine junctional zone smooth muscle cells via the let‑7a/Lin28B axis in adenomyosis
Molecular medicine reports ·doi:10.3892/mmr.2021.11976

The estrogen 17β‑estradiol has been proven to serve an indispensable role in the occurrence and development of adenomyosis (ADS). The let‑7a/Lin28B axis can control cell proliferation by acting as a tumor‑inhibiting axis in numerous types o…

lab-animal 2021
Talin1 Induces Epithelial-Mesenchymal Transition to Facilitate Endometrial Cell Migration and Invasion in Adenomyosis Under the Regulation of microRNA-145-5p
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-020-00444-8

Adenomyosis (ADS) is a commonly encountered benign gynecological disorder. Epithelial-mesenchymal transition (EMT) may serve a pivotal role in the pathogenesis of ADS. Talin1 has been identified to be implicated in multiple human carcinomas…

lab-animal 2021
Upregulated microRNA let-7a accelerates apoptosis and inhibits proliferation in uterine junctional zone smooth muscle cells in adenomyosis under conditions of a normal activated hippo-YAP1 axis
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-021-00753-w

BACKGROUND: Let-7a is a small non-coding RNA that has been found to take part in cell proliferation and apoptosis. The hippo-YAP1 axis, known as a tumour suppressor pathway, also plays an important role in cell proliferation and apoptosis. …

lab-animal 2021
Upregulated Talin1 synergistically boosts β-estradiol-induced proliferation and pro-angiogenesis of eutopic and ectopic endometrial stromal cells in adenomyosis
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-021-00756-7

Adenomyosis (ADS) is an estrogen-dependent gynecological disease with unspecified etiopathogenesis. Local hyperestrogenism may serve a key role in contributing to the origin of ADS. Talin1 is mostly identified to be overexpressed and involv…

lab-animal 2021
Upregulated Talin1 Synergistically Boosts β-estradiol-induced Proliferation and Pro-angiogenesis of Eutopic and Ectopic Endometrial Stromal Cells in Adenomyosis
·doi:10.21203/rs.3.rs-181716/v1

Abstract Adenomyosis (ADS) is an estrogen-dependent gynecological disease with unspecified etiopathogenesis. Local hyperestrogenism may serve a central role in contributing the origin of ADS. Talin1 is mostly identified to be overexpressed …

observational 2020
[Expression and significance of chemokine CXCL12 and receptor CXCR4 in adenomyosis]
Zhonghua fu chan ke za zhi ·doi:10.3760/cma.j.cn112141-20200226-00140

Objective: To observe the expression, correlation and significance of chemokine (C-X-C motif) ligand 12 (CXCL12) and chemokine (C-X-C motif) receptor 4 (CXCR4) in endometrium and myometrium of adenomyosis. Methods: Totally 38 patients were …