Kathy L. Sharpe-Timms

ORCID: 0000-0002-4708-1309 · 56 papers in corpus
rct 1998
Tissue inhibitor of metalloproteinase-1 concentrations are attenuated in peritoneal fluid and sera of women with endometriosis and restored in sera by gonadotropin-releasing hormone agonist therapy
Fertility and sterility ·doi:10.1016/s0015-0282(98)00075-2

OBJECTIVE: To establish tissue inhibitor of metalloproteinase-1 (TIMP-1) concentrations in peritoneal fluid (PF) and sera of women with endometriosis and compare them to disease-free controls. DESIGN: Prospective randomized study. SETTING…

review 1997
Basic research in endometriosis
Obstetrics and Gynecology Clinics of North America ·doi:10.1016/s0889-8545(05)70304-1

A more thorough understanding of the mechanisms associated with the cause and pathophysiology of endometriosis may help in the development of new diagnostic and therapeutic methods for the management of endometriosis. Research has begun to …

1997
O-134 Gonadotrophin-releasing hormone agonist (GnRHa) therapy alters activity of plasminogen activators (PA), Matrix Metalloproteinases (MMP) and of their inhibitors (PAI and MMPI) in rat models for adhesion formation and endometriosis: Potential GnRHa-regulated mechanisms reducing adhesion formation
·doi:10.1016/s0015-0282(97)90766-4
lab-animal 1995
Partial purification and amino acid sequence analysis of endometriosis protein-II (ENDO-II) reveals homology with tissue inhibitor of metalloproteinases-1 (TIMP-1)
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jcem.80.12.8530636

De novo synthesized endometriosis protein-II (ENDO-II; M(r) 28,000 to 32,000; pI 7.0 to 9.0) was partially purified from rat endometriotic tissue culture media using affinity chromatography and two-dimensional SDS-PAGE. The protein was elec…

1995
Partial purification and amino acid sequence analysis of endometriosis protein-II (ENDO-II) reveals homology with tissue inhibitor of metalloproteinases-1 (TIMP-1)
·doi:10.1210/jc.80.12.3784
other 1994
Immunohistochemical localization of granulocyte-macrophage colony-stimulating factor in matched endometriosis and endometrial tissues
American journal of obstetrics and gynecology ·doi:10.1016/0002-9378(94)90091-4

OBJECTIVE: Murine endometrial granulocyte-macrophage colony-stimulating factor has been related to macrophage recruitment and activation and postulated to mediate reproductive events. This study was designed to determine whether granulocyte…