Teixeira JM

No ORCID on file · 6 papers in corpus · active 2019-2025
2025
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-025-01893-9

Uterine fibroids, or leiomyomas, are noncancerous tumors of the myometrium and the most common tumors in women, with a cumulative incidence of approximately 80% by age 50. Currently, hysterectomy is the only definitive cure, and effective n…

2023
Carcinogenesis ·doi:10.1093/carcin/bgac101

Loss of heterozygosity and promoter hypermethylation of APC is frequently observed in human endometrial cancer, which is the most common gynecological cancer in the USA, but its carcinogenic driver status in the endometrial epithelium has n…

2023
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-023-01094-6

Endometrial epithelia are known to harbor cancer driver mutations in the absence of any pathologies, including mutations in PIK3CA. Insulin plays an important role in regulating uterine metabolism during pregnancy, and hyperinsulinemia is a…

2022
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-022-01030-0

Obesity impacts fertility and is positively correlated with endometrial hyperplasia and endometrial cancer occurrence. Endometrial epithelia often harbor disease driver-mutations, while endometrial stroma are highly regulative of neighborin…

2021
International journal of molecular sciences ·doi:10.3390/ijms22073618

Uterine fibroid tissues are often compared to their matched myometrium in an effort to understand their pathophysiology, but it is not clear whether the myometria of uterine fibroid patients represent truly non-disease control tissues. We a…

2019
Purinergic signalling ·doi:10.1007/s11302-019-09659-0

P2X3 receptors are involved with several pain conditions. Muscle pain induced by static contraction has an important socioeconomic impact. Here, we evaluated the involvement of P2X3 receptors on mechanical muscle hyperalgesia and neutrophil…