It is well known that endometriosis is associated with an increase in the risk of deep dyspareunia, with potential negative effects on global female sexual functioning and couple relationship. The aims of this study were to review the liter…
Endometriosis is characterized by frequent recurrences of symptoms and lesions even after extirpative surgery. Because medical therapies control but do not cure the disease, long periods of pharmacologic management may be needed until pregn…
Endometriosis is an estrogen-dependent chronic inflammatory disease, defined by the presence of endometrial glands and stroma at ectopic sites. A rare and life-threatening complication associated with endometriosis is represented by spontan…
Deep endometriosis, occurring approximately in 1% of women of reproductive age, represents the most severe form of endometriosis. It causes severe pain in the vast majority of affected women and it can affect the bowel and the urinary tract…
Vitamin D is a fat-soluble pro-hormone that plays an important role in bone homeostasis; beside this principal function, vitamin D promotes modulation of cell growth, neuromuscular and immune function, and reduction of inflammation. In addi…
The relationship between rectovaginal-bowel endometriosis and fertility is unclear. Nevertheless, extirpative surgery, including colorectal resection, is being fostered as a fertility-enhancing procedure. Adenomyosis and deep endometriosis …
Endometriosis is influenced by both genetic and environmental factors. Genetic factors make up about half of the variation in endometriosis. Nevertheless, the genetics of endometriosis remains complex and in part unsolved, but recently, bas…
STUDY QUESTION: Is the prevalence of blue eye colour higher in women with deep endometriosis? SUMMARY ANSWER: Blue eye colour is more common in women with deep endometriosis when compared with both women with ovarian endometriomas and wome…
The presence of a primary endometrioma and its surgical excision may be detrimental for future fertility. After removal of the primary tumor, recurrence is common: 30% to 50% after 2 to 5 years of follow-up. The likelihood of conception aft…
OBJECTIVE: To evaluate physical attractiveness in women with and without endometriosis. DESIGN: Case-control study. SETTING: Academic hospital. PATIENT(S): Three hundred nulliparous women. INTERVENTION(S): Assessment of attractiveness b…
Analysis of published series reveals that no more than a fourth of subfertile patients undergoing surgery for peritoneal endometriotic implants, rectovaginal endometriotic lesions, or recurrent endometriomas achieved conception spontaneousl…
The effect of rectovaginal endometriosis on fertility is unclear. Several authors foster radical surgery, including colorectal resection, as a fertility-enhancing procedure. However, interpretation of data is difficult, as the baseline fert…
OBJECTIVE: To assess the impact of rectovaginal endometriosis on pain at intercourse and sexual functioning. DESIGN: Case-control study. SETTING: Academic department. PATIENT(S): Case subjects were women with rectovaginal endometriosis (…
Ovulation seems crucial in the pathogenesis of ovarian endometriomas. Therefore, suppression of ovulation should be protective against cyst relapse after excision. The objective of this systematic review was to assess the effect of long-ter…
Serous, endometrioid, clear cell and mucinous histotypes are the most common epithelial ovarian cancer. Most serous cancers appear to originate from precursor lesions at the fimbriated tubal end, whereas most endometrioid and clear cell can…