Sakthivignesh Ponandai-Srinivasan

No ORCID on file · 4 papers in corpus · active 2018-2023

Study types

  • article 2
  • other 1
  • review 1

Condition tags

  • mesh:D004715 3
  • endometriosis 3
  • endometrioma 2
  • infertility 1
  • adenomyosis 1
article 2023
Bromocriptine inhibits proliferation in the endometrium from women with adenomyosis
Frontiers in endocrinology ·doi:10.3389/fendo.2023.1026168

Objective Bromocriptine treatment has been shown to reduce menstrual bleeding and pain in women with adenomyosis in a pilot clinical trial. The underlying mechanism contributing to the treatment effect is however unknown. The purpose of thi…

article 2020
Syndecan-1 modulates the invasive potential of endometrioma via TGF-β signalling in a subgroup of women with endometriosis
Human Reproduction ·doi:10.1093/humrep/deaa164

STUDY QUESTION: What is the physiological role of transforming growth factor-beta (TGF-β1) and syndecans (SDC1, SDC4) in endometriotic cells in women with endometriosis? SUMMARY ANSWER: We observed an abnormal, pro-invasive phenotype in a s…

other 2018
Aberrant expression of genes associated with stemness and cancer in endometria and endometrioma in a subset of women with endometriosis
Human Reproduction ·doi:10.1093/humrep/dey241

STUDY QUESTION: Is there molecular evidence for a link between endometriosis and endometriosis-associated ovarian cancers (EAOC)? STUDY ANSWER: We identified aberrant gene expression signatures associated with malignant transformation in a…

review 2018
DNA methylation alterations—potential cause of endometriosis pathogenesis or a reflection of tissue heterogeneity?†
Biology of reproduction ·doi:10.1093/biolre/ioy067

Alterations in the DNA methylation pattern of endometriotic lesions and endometrium of endometriosis patients have been proposed as one potential factor accompanying the endometriosis development. Although many differentially methylated gen…