Some patterns of uterine adenomyosis (AM) are more common in China than Europe or USA. In this new classification derived from clinical observations in Shanghai, there are four patterns of adenomyosis, and, three out of the four have neurol…
The hypothesis is that many clinical conditions in obstetrics and gynaecology result from the diverse and varying consequences of injuries to pelvic autonomic nerves. These injuries result from difficult first labours, persistent physical e…
Xia, Wei Ting MD; Cai, Yao Yao MD; Yang, Si Meng MD; Wu, Xue Qing MD; Quinn, Martin J. MD, LLM Author Information
Annals of Surgery: June 2013 - Volume 257 - Issue 6 - p e17 doi: 10.1097/SLA.0b013e31828d6fd8
Difficult intrapartum episodes and persistent straining during defecation cause injuries to uterine nerves and uterosacral ligaments. Injuries to uterine nerves (denervation) result in loss of fundocervical polarity, uterotubal dysmotility …
Recent gynaecological studies show that childbirth, constipation, trauma and surgery cause injuries to autonomic nerves at different anatomical sites in the female pelvis resulting in endometriosis, adenomyosis and fibroids. Re-growth of ab…
The denervation-reinnervation view proposes that retrograde menstruation results from loss of normal, fundocervical polarity caused by injuries to uterine nerves. Injuries may be sporadic (following vaginal delivery) or recurrent (after per…
Four clinical cases are described in which a history of straining to achieve defaecation over many years, was associated with prolonged pelvic pain and the neuro-immunohistochemical observation of perivascular nerve fibre proliferation (PVN…
This study describes the innervation of the uterus with a histopathological diagnosis of adenomyosis in a retrospective survey of two groups of uteri. Group 1 consisted of 17 histologically-normal, parous uteri and eight nulliparous uteri. …
ObjectiveChronic pelvic pain is associated with a wide range of clinical conditions that include endometriosis. The precise cause, mechanisms of pain, and natural history are imprecise. Patterns of uterine innervation have been studied afte…
Endometriosis describes endometrium found outside the uterine cavity and is frequently associated with clinical presentations of chronic pelvic pain, dysmenorrhoea, dyspareunia and subfertility. It was originally attributed to retrograde me…
Difficult vaginal deliveries damage branches of the inferior hypogastric plexus as they are distributed to the pelvic viscera. The initial denervatory injury is often asymptomatic. Nerve fibre proliferation along the course of damaged nerve…
"Uterine nerve fibre proliferation in advanced endometriosis." Journal of Obstetrics and Gynaecology, 24(8), pp. 932–933