Dong Y

ObjectivesThe research aims to leverage machine learning techniques to better understand the diagnosis of myofascial pelvic pain syndrome (MPPS) and to develop useful tools for clinical practice.MethodsThis study retrospectively analyzed cl…

Research on the association between urinary heavy metals, phthalates, phytoestrogens (PEs), polycyclic aromatic hydrocarbons (PAHs), and endometriosis (EM) is limited. Data were from the National Health and Nutrition Examination Survey 1999…

Conventional in vitro fertilization (IVF) outcome prediction is limited by static, single-endpoint analyses. We aimed to overcome this by using a multistate model to dissect the stage-specific and, crucially, the non-linear influence of end…

Evidence remains unknown regarding the associations between PM2.5 and its components exposure and dynamic progression of different assisted reproductive outcomes in participants undergoing fresh embryo transfer. We included infertile partic…

BACKGROUND: Endometriosis is common in reproductive-age women, but the development of an endometriotic cyst that mimics tumor recurrence during follow-up after treatment for ovarian immature teratoma poses a significant diagnostic challenge…

N 6-methyladenosine (m6A) and N6, 2'-O-dimethyladenosine (m6Am) are two RNA modifications that play essential roles in diverse RNA metabolic processes and functions. Despite their importance, the dynamic landscapes and regulatory patterns o…

OBJECTIVES: To explore the clinical relevant factors of patients with recurrent and non-recurrent abdominal wall endometriosis after surgical treatment, to further study the relevant risk factors of abdominal wall endometriosis recurrence, …

Endometrium, the lining of the uterus, changes dynamically in response to fluctuations in ovarian hormones. The proper endocrine environment regulates endometrial functions: menstruation and supporting pregnancy. Obesity is closely related …

BackgroundMyofascial pelvic pain syndrome (MPPS) is a common but often underdiagnosed cause of chronic pelvic pain in women, significantly affecting quality of life. Early and accurate identification of patients at risk is essential for imp…

The study aimed to investigate the expression of nuclear actor-k-gene binding(NF-κB) and immediate early response 3(IER3) in ovarian endometrioid cysts and its correlation with the recurrence of the ovarian endometrioid cyst. From January 2…

Chronic widespread pain (CWP) remains challenging due to its heterogeneous causes and complex mechanisms. A total of 2920 plasma proteins are analyzed from 29,254 UK Biobank participants. A total of 256 proteins are identified as cross-sect…

Whether and how endometrial aging affects fertility remains unclear. In our in-house clinical cohort at the Center for Reproductive Medicine of Peking University Third Hospital (n = 1,149), we observed adverse pregnancy outcomes in the midd…

Ya-Xing Fang,1– 3,* Yu-Feng He,1– 3,* Bing-Bing Wang,1– 3,* Juan He,1,2 Yang Dong,1,2 Guo Chen,1– 3 Shu-Guang Zhou3– 6 1Department of Obstetrics and Gynecology, Maternity and Child Healthcare Hospital Affiliated to Anhui Medical…

BACKGROUND: Endometriosis (EM), a prevalent gynecological disorder in reproductive-age women, lacks reliable noninvasive diagnostic tools. EM may be detected by neutrophil extracellular traps (NETs), which are essential to inflammation and …

Levonorgestrel intrauterine-releasing system (LNG-IUS), an intrauterine device, is recommended for patients with adenomyosis; however, it often shows poor outcomes in these patients because of their large uterine size. This prospective stud…

PURPOSE: Endometriosis (EM) and recurrent spontaneous abortion (RSA) exhibit clinical associations, yet their shared molecular mechanisms remain unclear. This study aimed to identify shared molecular mechanisms and potential hub genes under…

BackgroundThe National Natural Science Foundation of China (NSFC) plays a pivotal role in supporting basic medical research and shaping national funding priorities. As clinical and scientific demands in obstetrics and gynecology grow, parti…

BackgroundTo compare in-vitro fertilization and embryo transfer (IVF-ET) pregnancy outcomes following endometrial polypectomy using either a manual mechanical hysteroscopic tissue resection device (mHTR) or traditional mechanical resection …

Nuclear receptors (NRs) are a large family of ligand-dependent transcription factors that regulate the expression of a wide range of target genes in response to endogenous and exogenous ligands, including steroid hormones, thyroid hormone, …

ObjectiveThis study aimed to explore the relationship between serum uric acid-to-serum creatinine (UA:SCr) ratio and thyroid function within the normal range and in gestational diabetes mellitus (GDM) during early pregnancy in Chinese women…

Oxidative stress (OS) refers to the production of a substantial amount of reactive oxygen species (ROS), leading to cellular and organ damage. This imbalance between oxidant and antioxidant activity contributes to various diseases, includin…

BACKGROUND: The chronic inflammatory immune response is a significant factor in the pathogenesis of benign gynecological diseases. The systemic immunoinflammatory index (SII) and the platelet-to-lymphocyte ratio (PLR) are commonly available…

Background and objectivesInfertility is a pressing public health concern on a national scale and has been linked to inflammatory conditions. However, limited research has been conducted on the impact of the Dietary Inflammatory Index (DII) …

STUDY OBJECTIVE: To investigate whether different timings of GnRH-a downregulation affected assisted reproductive outcomes in infertile women with moderate-to-severe intrauterine adhesions (IUAs) accompanied by adenomyosis. DESIGN: A retro…

Background: Growing evidence suggests that endometriosis (EMs) is a risk factor for endometriosis-associated ovarian cancer (EAOC). The aim was to identify and validate gene signatures associated with EMs that may serve as potential biomark…