Joel Castro

No ORCID on file · 10 papers in corpus · active 2019-2025

Study types

  • article 6
  • book-chapter 1
  • other 1
  • preprint 1
  • review 1

Condition tags

  • endometriosis 10
  • chronic_pelvic_pain 7
  • irritable_bowel_syndrome 3
  • infertility 2
  • dyspareunia 1
other 2025
bioRxiv : the preprint server for biology ·doi:10.1101/2025.10.20.683510

Endometriosis is a painful gynecological inflammatory disease affecting up to 10% of females. When released by sensory neurons, calcitonin gene-related peptide (CGRP) shapes immunity, a process known as neuroimmune communication. We previou…

article 2023
Journal of neurochemistry ·doi:10.1111/jnc.15843

Chronic pelvic pain (CPP) is the most debilitating symptom of gynaecological disorders such as endometriosis. However, it remains unclear how sensory neurons from pelvic organs affected by endometriosis, such as the female reproductive trac…

book-chapter 2023
·doi:10.1007/978-3-031-25702-5_16
article 2023
Journal of neurochemistry ·doi:10.1111/jnc.15795

Chronic pelvic pain (CPP) is the primary symptom of endometriosis patients, but adequate treatments are lacking. Modulation of ion channels expressed by sensory nerves innervating the viscera has shown promise for the treatment of irritable…

preprint 2022
·doi:10.1101/2022.10.06.511228

Abstract Chronic pelvic pain (CPP) is the primary symptom of endometriosis patients, but adequate treatments are lacking. Modulation of ion channels expressed by sensory nerves innervating the viscera have shown promise for the treatment of…

article 2021
FASEB journal : official publication of the Federation of American Societies for Experimental Biology ·doi:10.1096/fj.202002441r

Endometriosis is a painful inflammatory disorder affecting ~10% of women of reproductive age. Although chronic pelvic pain (CPP) remains the main symptom of endometriosis patients, adequate treatments for CPP are lacking. Animal models that…

article 2021
Pain ·doi:10.1097/j.pain.0000000000002552

ABSTRACT: Endometriosis is a chronic and debilitating condition, commonly characterised by chronic pelvic pain (CPP) and infertility. Chronic pelvic pain can be experienced across multiple pelvic organs, with comorbidities commonly effectin…

review 2020
Frontiers in cellular neuroscience ·doi:10.3389/fncel.2020.590823

Endometriosis is a chronic and debilitating condition affecting ∼10% of women. Endometriosis is characterized by infertility and chronic pelvic pain, yet treatment options remain limited. In many respects this is related to an underlying la…

article 2020
Pain ·doi:10.1097/j.pain.0000000000002036

Dyspareunia, also known as vaginal hyperalgesia, is a prevalent and debilitating symptom of gynaecological disorders such as endometriosis and vulvodynia. Despite this, the sensory pathways transmitting nociceptive information from female r…

article 2019
Pain ·doi:10.1097/j.pain.0000000000001657

Endometriosis, an estrogen-dependent chronic inflammatory disease, is the most common cause of chronic pelvic pain. Here, we investigated the effects of linaclotide, a Food and Drug Administration-approved treatment for IBS-C, in a rat mode…