Yamada-Nomoto K

No ORCID on file · 4 papers in corpus · active 2016-2020

Study types

  • article 4

Condition tags

  • endometriosis 4
  • endometrioma 1
article 2020
Relaxin-2 May Suppress Endometriosis by Reducing Fibrosis, Scar Formation, and Inflammation
Biomedicines ·doi:10.3390/biomedicines8110467

Background: Relaxin (RLX)-2, produced by the corpus luteum and placenta, is known to be potentially effective in fibrotic diseases of the heart, lungs, kidneys, and bladder; however, its effectiveness in endometriosis has not yet been inves…

article 2019
Sphingosine I Phosphate (S1P) Increased IL-6 Expression and Cell Growth in Endometriotic Cells
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719119828112

ObjectsThere is growing evidence that sphingosine 1-phosphate (S1P) is involved in inflammatory diseases. As endometriosis is known as an inflammatory disease, we investigated the role of S1P system in the development of endometriosis.Metho…

article 2017
Bradykinin system is involved in endometriosis‐related pain through endothelin‐1 production
European journal of pain (London, England) ·doi:10.1002/ejp.1133

BACKGROUND: Endometriosis is a gynaecological disease exhibiting severe pelvic pain, but the mechanism of pain production remains unknown. Bradykinin (BK) is known as an inflammatory mediator, and shows elevated levels in inflammatory disea…

article 2016
Alpha‐7 nicotinic acetylcholine receptor (nAChR) agonist inhibits the development of endometriosis by regulating inflammation
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/aji.12592

OBJECTIVE: We investigated α-7 nAchR expression in human peritoneal macrophages and examined whether activation of nAchR might be a new therapy for endometriosis. MATERIALS AND METHODS: Human peritoneal fluid mononuclear cells (PFMC) were s…