Moncef Benkhalifa

OBJECTIVE: Endometriosis remains an underdiagnosed gynecological condition due to the lack of validated non-invasive biomarkers. This study aimed to evaluate the diagnostic value of plasma interleukin-6 (IL-6), serum cancer antigen 125 (CA1…

Background: Endometriosis is a systemic chronic disease affecting seriously various aspects of fe-male health and wellbeing. It was shown to be associated with a significant increase of free circulating DNA (fcDNA) and gene methylation prof…

Endometriosis is a chronic, estrogen-dependent disorder associated with the presence of endometrial cells mainly in the pelvic cavity, causing systemic immune inflammation, infertility, epigenetic dysregulation of differential DNA methylati…

Over the last decades, human infertility has become a major concern in public health, with severe societal and health consequences. Growing evidence shows that endocrine disruptors chemicals (EDCs) have been considered as risk factors of in…

International audience

International audience

To date, the pathogenesis of endometriosis related infertility is still poorly understood. In particular, impaired oocyte quality, parameter that remains difficult to assess in current practice could be implicated in this infertility. The o…

The negative impact of endocrine-disrupting pesticides on human fertility is now a key issue in reproductive health. There are much fewer literature data about the impact of pesticide exposure on women than on men and very few studies of wo…

The intrauterine insemination with husband's sperm is an assisted reproductive technologie, as proposed in the case of cervical infertility, moderate male infertility, dysovulation, mild or moderate endometriosis or unexplained infertility.…