David Piquemal

ORCID: 0000-0002-5870-4276 · 3 papers in corpus
article 2026
Effect of deoxyribonuclease I therapy on free circulating DNA level and gene methylation profile changes in patients with endometriosis: Proof of concept and preliminary data
Science progress ·doi:10.1177/00368504261479982

ObjectiveEndometriosis is a systemic chronic disease with serious effects on various aspects of female health and wellbeing that has been associated with a significant increase in free circulating DNA (CfDNA) and gene methylation profile ch…

preprint 2025
Effect of Deoxyribonuclease I Therapy on Free Circulating DNA Level and Gene Methylation Profile Changes in Patients with Endometriosis: Preliminary Data
·doi:10.20944/preprints202512.1221.v1

Background: Endometriosis is a systemic chronic disease affecting seriously various aspects of fe-male health and wellbeing. It was shown to be associated with a significant increase of free circulating DNA (fcDNA) and gene methylation prof…

other 2025
Quantification of Free Circulating DNA and Differential Methylation Profiling of Selected Genes as Novel Non-Invasive Biomarkers for Endometriosis Diagnosis
Biomolecules ·doi:10.3390/biom15010069

Endometriosis is a chronic, estrogen-dependent disorder associated with the presence of endometrial cells mainly in the pelvic cavity, causing systemic immune inflammation, infertility, epigenetic dysregulation of differential DNA methylati…