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Endometriosis (EMs), a significant global health issue, characterized by unclear pathogenesis, nonspecific symptoms, and poor treatment outcomes. The organ-on-chip technology has achieved great advances in disease modeling, yet its potentia…
BACKGROUND: Palmitoylation, a post-translational lipid modification, has garnered increasing attention for its role in inflammatory processes and tumorigenesis. Emerging evidence suggests a potential association between palmitoylation and i…
Endometriosis is an estrogen-dependent disorder of the reproductive tract, affecting approximately 10 % of women. The symptoms of this condition are vague and not correlated with the disease's stage. These associated symptoms significantly…
Endometriosis is an inflammation-dependent disease that shares similarities with malignant tumors including attachment and infiltration. Tripartite motif-containing 24 (TRIM24) has been illustrated in inflammatory responses and gynecologica…
To observe the effect of Cai's Neiyi Prescription (CNYP) on the apoptosis and inflammation in endometrial stromal cells with endometriosis (EM) both in vivo and in vitro, EM model rats and endometrial stromal cells were treated with CNYP an…
Endometriosis has been initially described as endometrial-like tissue outside of the uterine cavity. The mitogen-activated protein kinase/ERK kinase (MEK)/extracellular signal-regulated kinase (ERK) signaling pathway playing an important ro…
Objective To study the expression of ER and PR in ectopic and eutopic endometrium in patients with endometriosis. Methods The expression of ER and PR in ectopic and eutopic endometrium were detected by immunohistochemistry SP method in 45 p…