R. Ann Word

No ORCID on file · 14 papers in corpus · active 2001-2018

Study types

  • article 14

Condition tags

  • endometriosis 8
  • endometrioma 2
article 2018
Effect of single-dose ibuprofen on follicular fluid levels of interleukins in poor responders undergoingin vitrofertilization
·doi:10.1080/19396368.2018.1557761

Premature follicular rupture during in vitro fertilization (IVF) is a well-known culprit for cycle cancellation. We sought to evaluate whether a single oral dose of ibuprofen will have an effect on the follicular fluid (FF) levels of inflam…

article 2017
Androgens Upregulate Endometrial Epithelial Progesterone Receptor Expression: Potential Implications for Endometriosis
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719117691145
article 2017
Endometrial stromal cell attachment and matrix homeostasis in abdominal wall endometriomas
Human Reproduction ·doi:10.1093/humrep/dex371

STUDY QUESTION: How does progesterone alter matrix remodeling in abdominal wall endometriomas compared with normal endometrium? SUMMARY ANSWER: Progesterone may prevent attachment of endometrial cells to the abdominal wall, but does not ame…

article 2014
Androgen regulation of progesterone receptor (PR) expression in endometrium: implications for endometriosis
·doi:10.1016/j.fertnstert.2014.07.270
article 2013
0013-7227/08/$15.00/0 Endocrinology 149(3):1190–1204 Printed in U.S.A. Copyright © 2008 by The Endocrine Society doi: 10.1210/en.2007-0665 Inflammatory Status Influences Aromatase and Steroid Receptor Expression in Endometriosis

ENDOMETRIOSIS IS AN estrogen-dependent disease associated with enhanced aromatase expression and local estrogen production in endometriotic tissues (1–3). Although retrograde menstruation with subsequent implantation and growth of endometri…

article 2013
Progesterone and transforming growth factor Beta 1 (tgfβ1) regulate matrix metalloproteinases (MMPs) in human normal endometrium and endometriosis
·doi:10.1016/j.fertnstert.2013.07.788
article 2012
Transforming Growth Factor β1 (TGFβ1) and Progesterone Regulate Matrix Metalloproteinases (MMP) in Human Endometrial Stromal Cells
·doi:10.1210/jc.2011-3073

CONTEXT: Menstruation is preceded by progesterone withdrawal and endometrial matrix remodeling predominantly through induction of matrix metalloproteinases (MMP) and recruitment of invading neutrophils. DESIGN: Using endometrial tissues fro…

article 2011
Effect of estradiol and transforming growth factor beta 1(TGFβ1) on expression of lysyl oxidase(LOX) in three-dimensional (3D) cocultures of human endometrium
·doi:10.1016/j.fertnstert.2011.07.568
article 2011
Transforming growth factor beta 1(TGFβ1) and progesterone differentially regulate matrix metalloproteinases (MMPs) in human normal endometrium and endometriosis
·doi:10.1016/j.fertnstert.2011.07.526
article 2010
Progesterone and transforming growth factor beta 1 (TGFB1) regulate matrix metalloproteinases (MMPS) in human endometrium
·doi:10.1016/j.fertnstert.2010.07.830
article 2008
Androstenedione Up-Regulation of Endometrial Aromatase Expression via Local Conversion to Estrogen: Potential Relevance to the Pathogenesis of Endometriosis
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2008-0248

CONTEXT: Up-regulation of aromatase expression in endometrial cells disseminated into the peritoneal cavity may enhance their survival via local estrogen synthesis, which may lead to endometriosis. The factors that mediate induction of arom…

article 2007
Inflammatory Status Influences Aromatase and Steroid Receptor Expression in Endometriosis
Endocrinology ·doi:10.1210/en.2007-0665

Aberrant up-regulation of aromatase in eutopic endometrium and implants from women with endometriosis has been reported. Aromatase induction may be mediated by increased cyclooxygenase-2 (COX-2). Recently, we demonstrated that progesterone …

article 2006
O-74
·doi:10.1016/j.fertnstert.2006.07.088
article 2001
Regulation of Uterine 5α-Reductase Type 1 in Mice1
·doi:10.1095/biolreprod65.5.1378

A null mutation in the murine gene encoding steroid 5 alpha-reductase type 1 (5 alpha R1) leads to failure of normal parturition at term. This observation, together with the finding that mRNA levels of uterine 5 alpha R1 increase significan…