Recurrent pregnancy loss (RPL) has become an important reproductive health issue worldwide. RPL affects about 2%-3% of reproductive-aged women, and makes serious threats to women's physical and mental health. However, the etiology of approx…
MiR-145 has been shown to suppress cell invasiveness and proliferation in endometriosis, whereas prostate cancer-associated transcript 1 (PCAT1) was reported to act as a sponge of miR-145 with one single-nucleotide polymorphism (SNP), rs710…
BACKGROUND: Polycystic ovarian syndrome (PCOS) is characterised by the clinical signs of oligo-amenorrhoea, infertility and hirsutism. Conventional treatment of PCOS includes a range of oral pharmacological agents, lifestyle changes and sur…
OBJECTIVE: To investigate the therapeutic mechanism of bazedoxifene, the third-generation selective ER modulator (SERM), on endometriosis lesions in a rat model. METHODS: Endometriosis was induced by transplanting pieces of endometrium fro…
Endometriosis involving intestinal mucosa is relatively uncommon. It poses a diagnostic challenge for clinicians and pathologists. We herein report a case of colonoscopic specimen revealing rectal mucosal endometriosis. A 39-year-old woman …
Objective To investigate the application value of Colorful Doppler Flow Imaging(CDFI) in differential diagnosis of uterine myoma and adenomyosis.Methods CDFI ultrasonography and blood changes of 866 cases uterine fibroids,uterine adenomyosi…
Objective To evaluate the uterine artery embolization for the treatment of adenomyosis of the clinical effect.Methods January 2008-January 2010 with uterine artery embolization for treatment of 69 cases of patients with adenomyosis,with ute…
Objective To investigate the role of chemokines in peritoneal fluid on pathogenesis of endometriosis(EM).Methods Monocyte chemoattractant protein-1(MCP-1),regulated upon activation normal T cell expressed and secreted(RANTES)contents in per…
BACKGROUND: Visualization and biopsy of suspicious peritoneum can confirm endometriosis. Endoscopic India ink tattooing can lead to peritoneum that visually mimics endometriosis. CASE: A woman with chronic pelvic pain and a history of trea…
Objective To observe the effects of melatonin on cytokines and nature kill cells in endometriosis rat models. Methods Rats were randomly divided into four groups, including normal control group(n=10), model control group(n=10), melatonin gr…