Wu Q

ORCID: 0000-0002-1670-1050 · 94 papers in corpus
other 2021
Bioengineered ·doi:10.1080/21655979.2021.2003943

The molecular mechanism that triggers polycystic ovary syndrome (PCOS) is mysterious. Abnormal development of ovarian granulosa cells (GCs) is one of the causes of PCOS. Herein, our study was carried out using RNA-seq to detect the differen…

observational 2021
Experimental and therapeutic medicine ·doi:10.3892/etm.2020.9463

Polycystic ovary syndrome (PCOS) affects 8-13% of reproductive-age females worldwide and mutations or aberrant expression of androgen receptor (AR) may cause the onset of this disease. In the present study, 258 samples from Han Chinese pati…

other 2021
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-021-00778-1

BACKGROUND: The mechanism of recurrent implantation failure (RIF) is unclear at present and poor endometrial receptivity may be one of the leading reasons. This study aims to construct a competing endogenous RNA (ceRNA) network and identify…

observational 2021
Frontiers in endocrinology ·doi:10.3389/fendo.2021.766601

PURPOSE: To evaluate the association of endometrial thickness (EMT) with obstetric and neonatal outcomes in women with polycystic ovary syndrome (PCOS). METHODS: A total of 1755 subfertile PCOS women with singleton livebirths after frozen-…

meta-analysis 2020
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences ·doi:10.3785/j.issn.1008-9292.2020.05.01

OBJECTIVE: To evaluate the efficacy of black cohosh extracts (BCE) in improving the low estrogen status induced by postoperative gonadotropin-releasing hormone agonist (GnRHa) in patients with endometriosis. METHODS: Randomized clinical co…

diagnostic-accuracy 2019
International Journal of Gynecology & Obstetrics ·doi:10.1002/ijgo.12949

OBJECTIVE: To assess the utility of hematologic, inflammatory, and immunologic biomarkers for differentiating between ovarian cancer and endometriosis. METHODS: Data were retrospectively reviewed from women diagnosed with ovarian cancer an…

observational 2019
The Journal of international medical research ·doi:10.1177/0300060519860680

OBJECTIVE: This study aimed to examine the relationship between the follicular output rate (FORT) and clinical outcomes in patients with polycystic ovarian syndrome (PCOS). METHODS: A total of 841 patients with PCOS undergoing in vitro fer…

observational 2019
Archives of medical science : AMS ·doi:10.5114/aoms.2019.85145

INTRODUCTION: Controlled ovarian hyperstimulation (COH) is essential for artificial reproduction technology (ART). This study aimed to evaluate the effects of a mild starting dosage of r-FSH ovarian stimulation after the modified prolonged …

lab-animal 2019
Gynecologic and obstetric investigation ·doi:10.1159/000502258

BACKGROUND/AIMS: The identification of new compound candidates for endometriosis treatment is needed. Cyclooxygenase-2 (COX-2) is considered a crucial target to control the progress and recurrence of endometriosis. Here, we identified ursol…

rct 2018
Reproductive health ·doi:10.1186/s12978-018-0639-8

BACKGROUND: Endometriosis is the major cause of progressive pelvic pain and subfertility. Up to 50% of reproductive-age women suffer from pelvic pain. Endometriosis is a classic indication for IVF. Compared with women whose inability to pro…

meta-analysis 2016
Experimental and therapeutic medicine ·doi:10.3892/etm.2016.3004

The present meta-analysis aimed to evaluate the effectiveness and safety of puerarin co-treatment with betahistine in treating vertebrobasilar ischemia (VBI) vertigo. A total of 6 medical databases were searched, identifying randomized cont…

lab-animal 2016
Journal of diabetes research ·doi:10.1155/2016/8541520

OBJECTIVE: Puerarin is a natural flavonoid isolated from the TCM lobed kudzuvine root. This study investigated the effect and mechanisms of puerarin on diabetic aorta in rats. METHODS: Streptozotocin- (STZ-) induced diabetic rats were admi…

other 2015
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719115572478

Endometriosis is a hormonal disease and also an inflammatory condition. Converging evidence indicates that inflammation and coagulation are 2 major host-defense systems that interact with each other. This study was undertaken to test the hy…

nonrandomized-trial 2015
Ultrasonics sonochemistry ·doi:10.1016/j.ultsonch.2015.05.024

OBJECTIVE: To evaluate the long-term improvement of clinical symptoms of adenomyosis after treatment with ultrasound-guided high intensity focused ultrasound (USgHIFU). METHODS: From January 2010 to December 2011, 350 patients with adenomy…

other 2015
Archives of gynecology and obstetrics ·doi:10.1007/s00404-015-3875-y

OBJECTIVE: To identify differentially expressed genes (DEGs) in endometriosis and further analyze molecular mechanisms implicated in disease pathogenesis. MATERIALS AND METHODS: Gene expression data (ID: GSE7846) of human endometrial endot…

rct 2014
European journal of radiology ·doi:10.1016/j.ejrad.2014.05.008

OBJECTIVE: To investigate the effects of oxytocin on high-intensity focused ultrasound (HIFU) ablation for the treatment of adenomyosis. MATERIALS AND METHODS: Eighty-six patients with adenomyosis from three hospitals were randomly assigne…

meta-analysis 2013
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology ·doi:10.3109/09513590.2013.819085

To assess the effects of oral contraceptive pills (OCPs) for endometriosis in women after conservative surgery, we performed a search of PubMed, Embase, ISI Web of Science, Cochrane Library, Scidirect, Chinese VIP, CNKI and WANGFANG databas…

case-report 2011
Gynecologic Oncology ·doi:10.1016/j.ygyno.2010.10.006
lab-animal 2010
Reproduction (Cambridge, England) ·doi:10.1530/rep-09-0390

The antral follicle constitutes a complex and regulated ovarian microenvironment that influences oocyte quality. Oxidative stress is a cellular state that may play a role during folliculogenesis and oogenesis, although direct supporting evi…