Atsushi Kiba

No ORCID on file · 4 papers in corpus · active 2010-2016

Study types

  • article 2
  • other 2

Condition tags

  • endometriosis 4
  • endometrioma 2
article 2016
Differential micro ribonucleic acid expression profiling in ovarian endometrioma with leuprolide acetate treatment
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.13137

AIM: Micro ribonucleic acids (miRNAs) play an important pathological role in endometriosis. Leuprolide acetate, an analog of gonadotropin-releasing hormone, is widely used to treat endometriosis; however, the molecular mechanisms involved i…

article 2015
Differential mRNA expression profiling in ovarian endometriotic tissue with versus without leuprolide acetate treatment
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.12768

AIM: Leuprolide acetate, an analog of gonadotropin-releasing hormone (GnRH), regresses endometriotic tissue and reduces pain, resulting in clinical improvement upon treatment. The molecular mechanisms involved in the regression of endometri…

other 2010
2-acylamino-4,6-diphenylpyridine derivatives as novel GPR54 antagonists with good brain exposure and in vivo efficacy for plasma LH level in male rats
Bioorganic & medicinal chemistry ·doi:10.1016/j.bmc.2010.05.061

GPR54 is a G protein-coupled receptor (GPCR) which was formerly an orphan receptor. Recent functional study of GPR54 revealed that the receptor plays an essential role to modulate sex-hormones including GnRH. Thus, antagonists of GPR54 are …

other 2010
Synthesis and structure-activity relationships of 2-acylamino-4,6-diphenylpyridine derivatives as novel antagonists of GPR54
Bioorganic & medicinal chemistry ·doi:10.1016/j.bmc.2010.04.036

GPR54 is a G protein-coupled receptor (GPCR) which was formerly an orphan receptor. Recent functional study of GPR54 revealed that the receptor has an essential role to modulate sex-hormones including GnRH. Though antagonists of GPR54 are e…