INTRODUCTION: La endometriosis es una enfermedad prevalente que causa dolor crónico e infertilidad, afectando significativamente la calidad de vida de las mujeres en edad reproductiva. El endometrioma, manifestación ovárica de la enfermedad…
Cell-free DNA fragments detected in blood and in other biological fluids are released from apoptotic/necrotic cells. In this study, we analyzed cfDNA levels in follicular fluid (FF) samples from patients with infertility. Samples were colle…
Oxidative stress has a fundamental role in the pathophysiology of various conditions, like infertility. This case-control study was performed to assess the potential role of CYP19A1, GSTM1, and GSTT1 in modifying individual predisposition t…
Due to its high prevalence, infertility has become a prominent public health issue, posing a significant challenge to modern reproductive medicine. Some clinical conditions that lead to female infertility include polycystic ovary syndrome (…
Endometriosis is a continuous and progressive disease with a poorly understood aetiology, pathophysiology and natural history. This study evaluated the histological differences between eutopic and ectopic endometria (abdominal wall endometr…
ObjectiveAdenosine deaminase acts on adenosine and deoxyadenosine metabolism and modulates the immune response. The adenosine deaminase G22A polymorphism (20q.11.33) influences the level of adenosine deaminase enzyme expression, which seems…
OBJETIVOS: verificar as freqüências dos genótipos nulos para os genes GSTT1 e GSTM1, assim como as freqüências do alelo polimórfico do gene CYP1A1 em um grupo de mulheres com endometriose, e comparar essas freqüências com aquelas observadas…