Khaled Zeitoun

No ORCID on file · 16 papers in corpus · active 1995-2013

Study types

  • article 12
  • review 3
  • book-chapter 1

Condition tags

  • endometriosis 15
  • infertility 1
article 2013
Chicken Ovalbumin Upstream Promoter Transcription Factor to the Same cis-Acting Element

In stromal cells of endometriosis, marked levels of aromatase P450 (P450arom) mRNA and activity are present and can be vigorously stimulated by (Bu) 2cAMP or PGE 2 to give rise to physiologically significant estrogen biosynthesis. Since eut…

article 2013
The Journal of Clinical Endocrinology & Metabolism Printed in U.S.A. Copyright © 2000 by The Endocrine Society Progesterone Receptor Isoform A But Not B Is Expressed in Endometriosis*

We previously demonstrated that 17 � hydroxysteroid dehydrogenase type 2, the enzyme that inactivates estradiol to estrone, is expressed in luteal eutopic endometrium in response to progesterone but not in simultaneously biopsied peritoneal…

article 2004
Inhibition of endometriosis development in rhesus monkeys by blocking VEGF receptor: A novel treatment for endometriosis
·doi:10.1016/j.fertnstert.2004.07.181
book-chapter 2003
Endometriosis
·doi:10.1016/b0-12-341103-3/00081-4
review 2000
Aromatase as a Therapeutic Target in Endometriosis
Trends in endocrinology and metabolism: TEM ·doi:10.1016/s1043-2760(99)00216-7
article 2000
Expression of dioxin-related transactivating factors and target genes in human eutopic endometrial and endometriotic tissues
American Journal of Obstetrics and Gynecology ·doi:10.1016/s0002-9378(00)70325-5
article 2000
Progesterone Receptor Isoform A But Not B Is Expressed in Endometriosis1
·doi:10.1210/jcem.85.8.6739

We previously demonstrated that 17β hydroxysteroid dehydrogenase type 2, the enzyme that inactivates estradiol to estrone, is expressed in luteal eutopic endometrium in response to progesterone but not in simultaneously biopsied peritoneal …

review 1999
Aromatase: a key molecule in the pathophysiology of endometriosis and a therapeutic target
Fertility and Sterility ·doi:10.1016/s0015-0282(99)00393-3
review 1999
Estrogen production in endometriosis and use of aromatase inhibitors to treat endometriosis.
Endocrine-related cancer ·doi:10.1677/erc.0.0060293

Estrogen is the most important known factor that stimulates the growth of endometriosis. Estrogen delivery to endometriotic implants was classically viewed to be only via the circulating blood in an endocrine fashion. We recently uncovered …

article 1999
Stimulation of Aromatase P450 Promoter (II) Activity in Endometriosis and Its Inhibition in Endometrium Are Regulated by Competitive Binding of Steroidogenic Factor-1 and Chicken Ovalbumin Upstream Promoter Transcription Factor to the Same cis-Acting Element
·doi:10.1210/me.13.2.239

In stromal cells of endometriosis, marked levels of aromatase P450 (P450arom) mRNA and activity are present and can be vigorously stimulated by (Bu)2cAMP or PGE2 to give rise to physiologically significant estrogen biosynthesis. Since eutop…

article 1999
Stimulation of Aromatase P450 Promoter (II) Activity in Endometriosis and Its Inhibition in Endometrium Are Regulated by Competitive Binding of Steroidogenic Factor-1 and Chicken Ovalbumin Upstream Promoter Transcription Factor to the Same cis-Acting Element
Molecular endocrinology (Baltimore, Md.) ·doi:10.1210/mend.13.2.0229

In stromal cells of endometriosis, marked levels of aromatase P450 (P450arom) mRNA and activity are present and can be vigorously stimulated by (Bu)2cAMP or PGE2 to give rise to physiologically significant estrogen biosynthesis. Since eutop…

article 1999
Use of Crinone∗ vaginal progesterone gel for luteal support in in vitro fertilization cycles
·doi:10.1016/s0015-0282(99)00362-3
article 1998
Deficient 17 -Hydroxysteroid Dehydrogenase Type 2 Expression in Endometriosis: Failure to Metabolize 17 -Estradiol
·doi:10.1210/jc.83.12.4474
article 1998
Deficient 17β-Hydroxysteroid Dehydrogenase Type 2 Expression in Endometriosis: Failure to Metabolize 17β-Estradiol1
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jcem.83.12.5301

Aberrant aromatase expression in stromal cells of endometriosis gives rise to conversion of circulating androstenedione to estrone in this tissue, whereas aromatase expression is absent in the eutopic endometrium. In this study, we initiall…

article 1998
Treatment of Severe Postmenopausal Endometriosis With an Aromatase Inhibitor
Fertility and Sterility ·doi:10.1016/s0015-0282(98)00022-3
article 1995
The role of color Doppler in diagnosis of endometriomas
Ultrasound in Obstetrics & Gynecology ·doi:10.1046/j.1469-0705.1995.05010051.x

The aim of this study was to characterize the appearance of the vascular pattern of endometriomas in terms of color Doppler and to verify the role of Doppler flow indices in differentiating endometriomas from other pelvic masses. Twenty pat…