Leppert PC

No ORCID on file · 12 papers in corpus · active 2006-2021

Study types

  • article 3

Condition tags

  • chronic_pelvic_pain 1
  • infertility 1
2021
F&S science ·doi:10.1016/j.xfss.2020.11.001

Scientists from multiple basic disciplines and an international group of physician-scientists from the field of obstetrics and gynecology presented recent studies and discussed new and evolving theories of uterine fibroid etiology, growth a…

2019
American journal of obstetrics and gynecology ·doi:10.1016/j.ajog.2018.10.032

BackgroundUterine leiomyomas (fibroid tumors) cause considerable symptoms in 30-50% of women and are the leading cause of hysterectomy in the United States. Women with uterine fibroid tumors often seek uterine-preserving treatments, but com…

2017
American journal of obstetrics and gynecology ·doi:10.1016/j.ajog.2016.12.177

BackgroundUterine fibroids are a common problem for reproductive-aged women, yet little comparative effectiveness research is available to guide treatment choice. Uterine artery embolization and magnetic resonance imaging-guided focused ult…

2016
Journal of Minimally Invasive Gynecology ·doi:10.1016/j.jmig.2015.12.012
2016
American journal of obstetrics and gynecology ·doi:10.1016/j.ajog.2016.04.001

BackgroundUterine fibroids are an important source of morbidity for reproductive-aged women. Despite an increasing number of alternatives, hysterectomies account for about 75% of all fibroid interventional treatments. Evidence is lacking to…

2015
F1000Research ·doi:10.12688/f1000research.6189.1

Uterine leiomyomas (fibroids) are the most prevalent medical problem of the female reproductive tract, but there are few non-surgical treatment options. Although many advances in the understanding of the molecular components of these tumors…

article 2012
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719111426603

BackgroundFew histopathologic studies of uterine wound healing have been published compared with similar healing in other tissues. Our objective was to examine the histopathology resulting from iatrogenic trauma to the myometrium to acquire…

2012
Human reproduction (Oxford, England) ·doi:10.1093/humrep/der436

BackgroundAlthough histological dating of endometrial biopsies provides little help for prediction or diagnosis of infertility, analysis of individual endometrial proteins, proteomic profiling and transcriptome analysis have suggested sever…

2012
Drug discovery today. Therapeutic strategies ·doi:10.1016/j.ddstr.2012.06.001

Uterine fibroids are common reproductive-age benign tumors that contribute to severe morbidity and infertility. Cumulative incidence is 4 times higher in Africian-Americans compared to Caucasians and constitutes a major health disparity cha…

2011
Fertility and sterility ·doi:10.1016/j.fertnstert.2011.06.062

ObjectiveTo present the rationale, design, and methodology of the Fibroid Interventions: Reducing Symptoms Today and Tomorrow (FIRSTT) study.DesignRandomized clinical trial.SettingTwo academic medical centers.Patient(s)Premenopausal women w…

article 2007
Journal of psychosomatic research ·doi:10.1016/j.jpsychores.2007.03.018

ObjectiveThe objective of this study was to assess the percentage of women scheduled for hysterectomy who would have liked to have had a child or more children and associated factors.MethodsThe study sample included 1140 premenopausal women…

article 2006
Fertility and sterility ·doi:10.1016/j.fertnstert.2006.06.050

We investigated the prevalence of abnormal screening results (questionnaire and testing for other causes of oligo-ovulation, male or tubal factor infertility) in a group of 1,313 oligo-ovulatory women (included and excluded subjects) whose …