Study types
- other 6
Condition tags
- endometriosis 6
Frequent coauthors
A murine peritoneal sclerosis scoring system was modified and adapted to the revised ASRM endometriosis staging system. Accordingly, anatomic landmarks in the region of the lesions were incorporated and weighted scores were assigned in acco…
(A) Endometriotic Lesions (circled) in Klf9-/- animals were either unchanged or had regressed in size from the time of initial peritoneal implantation, when evaluated at necropsy 3 weeks later. (B) Endometriotic lesions in these animals als…
(A) Pooled Human Organ-specific RNA (1 µg/reaction) was analyzed for KLF11 mRNA expression by PCR. mRNA levels of the housekeeping gene GAPDH were simultaneously assessed as loading control. Relative organ-specific KLF11 mRNA expression lev…
Endometriotic lesions in Klf11-/- mice were associated with prolific de novo scar tissue formation in contrast to wildtype controls. (A) Adhesions in Klf11-/- animals were thick, opaque, dense and unyielding to mechanical disruption by pres…
(A) Collagen 1A1 mRNA expression levels were determined from one of two endometriotic implants in each animal (Klf11-/- and wildtype). Col1a1 mRNA expression levels were increased 7.55±0.48 fold (p<0.05) in implants from Klf11-/- animals co…
(A) Endometriosis was surgically induced in 8 week old Klf11-/- and wildtype female mice (N = 7/group). All animals were weighed prior to initial surgery and at necropsy 3 weeks later. There was no difference in weight between the groups ei…