Xavier Santamaria

No ORCID on file · 7 papers in corpus · active 2012-2023

Study types

  • article 6
  • review 1

Condition tags

  • endometriosis 7
  • infertility 2
  • die_deep_infiltrating 1
article 2023
Global endometrial DNA methylation analysis reveals insights into mQTL regulation and associated endometriosis disease risk and endometrial function
Communications biology ·doi:10.1038/s42003-023-05070-z

Endometriosis is a leading cause of pain and infertility affecting millions of women globally. Herein, we characterize variation in DNA methylation (DNAm) and its association with menstrual cycle phase, endometriosis, and genetic variants t…

article 2019
Endometrial Stromal Cells Circulate in the Bloodstream of Women with Endometriosis: A Pilot Study
International journal of molecular sciences ·doi:10.3390/ijms20153740

Endometriosis is characterized by the presence of endometrial tissue outside the uterus. While endometriotic tissue is commonly localized in the pelvic cavity, it can also be found in distant sites, including the brain. The origin and patho…

article 2019
Macrophages display proinflammatory phenotypes in the eutopic endometrium of women with endometriosis with relevance to an infectious etiology of the disease
Fertility and sterility ·doi:10.1016/j.fertnstert.2019.08.060
article 2018
Lgr5 Does Not Vary Throughout the Menstrual Cycle in Endometriotic Human Eutopic Endometrium
International journal of molecular sciences ·doi:10.3390/ijms20010022

Endometriosis is characterized by the abnormal presence of endometrium outside of the uterus, resulting in pelvic pain and infertility. The leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5) has been postulated to be a marke…

article 2017
Aberrant expression of epithelial leucine-rich repeat containing G protein–coupled receptor 5–positive cells in the eutopic endometrium in endometriosis and implications in deep-infiltrating endometriosis
Fertility and sterility ·doi:10.1016/j.fertnstert.2017.08.018
review 2014
MicroRNA and gynecological reproductive diseases
Fertility and sterility ·doi:10.1016/j.fertnstert.2014.04.044
article 2012
Migration of Cells from Experimental Endometriosis to the Uterine Endometrium
Endocrinology ·doi:10.1210/en.2012-1202

Endometriosis is the estrogen-dependent growth of endometrial tissue outside the uterus. Endometriosis has an effect on the eutopic endometrium; however, the nature of the cellular or molecular signal from the lesion to the uterus is unknow…