Study types
- article 4
- review 2
Condition tags
- endometriosis 6
Top journals
Frequent coauthors
- Zhihong Lin 6
- Serdar E. Bulun 6
- You-Hong Cheng 5
- Cheng YH 4
- Bulun SE 4
- Magdy P. Milad 4
- Lin Z 4
- Trukhacheva E 4
- Edmond Confino 3
- Erkut Attar 3
Loss of progesterone signaling in the endometrium may be a causal factor in the development of endometriosis, and progesterone resistance is commonly observed in women with this disease. In endometriotic stromal cells, the levels of progest…
CONTEXT: Estradiol and its nuclear receptors, estrogen receptor (ER) alpha and ERbeta, play critical roles in endometrium and endometriosis. Levels of ERbeta, due to pathological hypomethylation of its promoter, are significantly higher in …
Endometriosis is a common and chronic disease characterized by persistent pelvic pain and infertility. Estradiol is essential for growth and inflammation in endometriotic tissue. The complete cascade of steroidogenic proteins/enzymes includ…
Local estrogen biosynthesis is a major factor in the pathogenesis of endometriosis. Aberrant expression of steroidogenic acute regulatory protein (StAR) and aromatase in endometriotic tissue leads to an up-regulation of estrogen production.…