Brudniewski HF

No ORCID on file · 3 papers in corpus · active 2015-2018

Study types

  • article 3

Condition tags

  • endometriosis 3
article 2018
Enhanced UGT1A1 Gene and Protein Expression in Endometriotic Lesions
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719118764255

The cellular function in endometriosis lesions depends on a highly estrogenic milieu. Lately, it is becoming evident that, besides the circulating levels of estrogens, the balance of synthesis versus inactivation (metabolism) of estrogens b…

article 2016
Increased expression of CYP1A1 and CYP1B1 in ovarian/peritoneal endometriotic lesions
Reproduction (Cambridge, England) ·doi:10.1530/rep-15-0581

Endometriosis is an estrogen-dependent disease affecting up to 10% of all premenopausal women. There is evidence that different endometriosis sites show distinct local estrogen concentration, which, in turn, might be due to a unique local e…

article 2015
Effects of steroid hormone on estrogen sulfotransferase and on steroid sulfatase expression in endometriosis tissue and stromal cells
The Journal of steroid biochemistry and molecular biology ·doi:10.1016/j.jsbmb.2015.12.025

Endometriosis is an estrogen-dependent disease that afflicts about 10% of women in their reproductive age, causing severe pain and infertility. The potential roles of female steroid hormones in modulating key estrogen-metabolizing enzymes, …