Shang L

No ORCID on file · 4 papers in corpus · active 2021-2024

Study types

  • article 1

Condition tags

  • endometriosis 1
article 2024
Microfluidics-derived hierarchical microparticles for the delivery of dienogest for localized endometriosis therapy
Acta biomaterialia ·doi:10.1016/j.actbio.2024.02.017

Drug therapy is one of the most important strategies for treating gynecological diseases. Local drug delivery is promising for achieving optimal regional drug exposure, considering the complex anatomy and dynamic environment of the upper ge…

2024
Oral Simnotrelvir for Adult Patients with Mild-to-Moderate Covid-19.
The New England journal of medicine ·doi:10.1056/nejmoa2301425

BackgroundSimnotrelvir is an oral 3-chymotrypsin-like protease inhibitor that has been found to have in vitro activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and potential efficacy in a phase 1B trial.MethodsIn…

2022
Integrated network pharmacology and experimental verification to investigate the mechanisms of YYFZBJS against colorectal cancer via CDK1/PI3K/Akt signaling.
Frontiers in oncology ·doi:10.3389/fonc.2022.961653

BackgroundColorectal cancer (CRC) is a common digestive tract malignancy with rising incidence and morbidity worldwide during recent years. Yi-Yi-Fu-Zi-Bai-Jiang-San (YYFZBJS), a traditional Chinese medicine formula, has showed positive eff…

2021
Progress in understanding the role of lncRNA in programmed cell death.
Cell death discovery ·doi:10.1038/s41420-021-00407-1

Long non-coding RNAs (lncRNAs) are transcripts longer than 200 nucleotides but not translated into proteins. LncRNAs regulate gene expressions at multiple levels, such as chromatin, transcription, and post-transcription. Further, lncRNAs pa…