OBJECTIVE: To evaluate the safety and pharmacokinetics/pharmacodynamics of AMY109, an anti-interleukin-8 recycling antibody in a first-in-human phase 1 trial in healthy volunteers (HVs) and patients with endometriosis. DESIGN: A multicente…
Peng-Hui Wang, an editorial board member at the International Journal of Gynecology and Obstetrics, had no role in the peer review process or decision to publish this article. The other authors declare that they have no conflicts of interes…
We have conducted cervical imaging of uterine and micro-vessel flow velocity waveforms in acute pelvic inflammatory disease (PID) by transvaginal power Doppler ultrasound (TVPDU) in order to explore the associations of sonographic parameter…
OBJECTIVE: To investigate the safety and efficacy of adjuvant gonadotropin-releasing hormone agonist (GnRH-a) treatment followed by maintenance dienogest (DNG) therapy after uterus-sparing surgery. METHODS: Retrospective cohort study. A to…
(Abstracted from J Minim Invasive Gynecol 2022;29:602–612) Endometriosis is one of the most common gynecologic disorders, affecting approximately 10% of reproductive-age women and presenting with dysmenorrhea, noncyclic pelvic pain, dyspare…
Adhesions, characterized by fibrin deposition leading to fibrous tissue connections (adherence tissues) between various tissue planes or organs, as part of internal healing process and inflammatory reactions passing through the different bu…
This study aims to analyze the patient profile and presentation of endometriosis-related hemorrhagic ascites and review its management to raise awareness among gynecologists and improve treatment strategies. We present a case report and eng…
OBJECTIVE: Endometriosis-associated epithelial ovarian cancer (EOC) often includes clear cell carcinoma and endometrioid-type carcinoma. Due to the low incidence of primary mucinous EOC and absence of association between endometriosis and p…
Clear cell carcinoma of the ovary (ovarian clear cell carcinoma [OvCCC]), one of subtypes of epithelial ovarian carcinoma (EOC), is often accompanied with endometriosis, which is also called as endometriosis-associated EOC (EAEOC) and frequ…
The use of weekly chemotherapy for the treatment of patients with advanced-stage serous-type epithelial Tubo-ovarian cancer (ETOC), and primary peritoneal serous carcinoma (PPSC) is acceptable as the front-line postoperative chemotherapy af…
Intrauterine adhesion (IUA), fibrosis, and scarring resulting from damage to the endometrium is a rare but serious clinical disease, contributing to a significant impairment of reproductive function. Uterine instrumentation, especially that…
Endometriosis is a multifactorial and chronic inflammatory disease, involving more than 10% of women of reproductive age, contributing to a heavy burden of socioeconomic health problems, such as pelvic adhesion, chronic pelvic pain, inferti…
Total hysterectomy (TH) may be one of the most frequent surgeries in women during their life-span period, although the recent trends have become more apparent in the use of fertility-sparing surgery (organ-preservation strategy) in place of…
Recurrent implantation failure (RIF) remains a clinical dilemma. Helium-Neon (He-Ne) laser irradiation has recently become more popular under certain clinical conditions. Given the unique therapeutic effects, we were interested in determini…
Polycystic ovary syndrome (PCOS) is a common endocrinopathy, characterized by chronic anovulation, hyperandrogenism, and multiple small subcapsular cystic follicles in the ovary during ultrasonography, and affects 5-10% of women of reproduc…
PurposeThe goal of the current study is to determine the risk of subsequent development of epithelial ovarian cancer (EOC) in women after ovarian surgery for benign ovarian tumors.Patients and methodsWe conducted the nationwide population-b…