Liqun Wang

No ORCID on file · 16 papers in corpus · active 2015-2025

Study types

  • article 13
  • preprint 2
  • other 1

Condition tags

  • endometriosis 10
  • adenomyosis 8
  • mesh:D004715 5
article 2025
Integrated analysis of single-cell and bulk transcriptomic data reveals altered cellular composition and predictive cell types in ectopic endometriosis
Frontiers in medicine ·doi:10.3389/fmed.2025.1641982

Background Endometriosis is often diagnosed late and presents significant challenges in clinical treatment. A comprehensive investigation of the cellular classification and composition of endometriosis is essential for studying its diagnosi…

preprint 2024
Integrated analysis of single-cell and bulk transcriptomic data reveals altered cellular composition and predictive cell types in endometriosis
·doi:10.21203/rs.3.rs-5277508/v1
article 2024
Oestrogen promotes the progression of adenomyosis by inhibiting CITED2 through miR-145
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2024.104108
article 2022
miR-218-5p in endometrial microenvironment prevents the migration of ectopic endometrial stromal cells by inhibiting LASP1
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-022-00928-z

BACKGROUND: Our previous two-dimensional electrophoresis experiment showed that the expression of LASP1 in patients with endometriosis was significantly higher than that of control endometrium. However, the molecular mechanism by which LASP…

article 2022
Whole-exome sequencing and functional validation reveal a rare missense variant in MMP7 that confers ovarian endometriosis risk
Human molecular genetics ·doi:10.1093/hmg/ddac062

Prior studies have shown that genetic factors play important roles in ovarian endometriosis. Herein, we first analyzed the whole-exome sequencing data from 158 patients with ovarian endometriosis and 385 local control women without endometr…

article 2021
Endometrial stromal cell proteomic analysis reveals LIM and SH3 protein 1 (LASP1) plays important roles in the progression of adenomyosis
Molecular human reproduction ·doi:10.1093/molehr/gaab008

Adenomyosis is one of the most common gynecological disorders that the molecular events underlying its pathogenesis remain not fully understood. Prior studies have shown that endometrial stromal cells (ESCs) played crucial roles in the path…

preprint 2021
miR-218-5p in Endometrial Microenvironment Prevents the Migration of Ectopic Endometrial Stromal Cells by Inhibiting LASP1
·doi:10.21203/rs.3.rs-600354/v1

Abstract Our previous two-dimensional electrophoresis experiments showed that the expression of LASP1 in patients with endometriosis was significantly higher than that of control endometrium. However, the molecular mechanism by which LASP1 …

article 2020
Suppression of PRDX4 inhibits cell proliferation and invasion of ectopic endometrial stromal cells in endometriosis
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology ·doi:10.1080/09513590.2020.1768369

Oxidative stress (OS) has been proposed to play a role in the development of EMs. Peroxiredoxins are a family of antioxidant proteins that exhibit peroxidase activity in a thioredoxin-dependent manner, protecting cells against OS. The Weste…

article 2019
Inhibition of formin like 2 promotes the transition of ectopic endometrial stromal cells to epithelial cells in adenomyosis through a MET-like process
Gene ·doi:10.1016/j.gene.2019.06.003
other 2018
GZFLW Induces Apoptosis of Ectopic Endometrial Stromal Cells via Promoting VPS53 Protein Stability
Evidence-based complementary and alternative medicine : eCAM ·doi:10.1155/2018/1293630

Endometriosis is still a major problem in obstetrics and gynecology. While GZFLW (Gui Zhi Fu Ling Wan) has been originally used for treating gynecological diseases, however, the molecular mechanism that GZFLW acts on endometriosis is not cl…

article 2018
Mutation analysis of ZP1, ZP2, ZP3 and ZP4 genes in 152 Han Chinese samples with ovarian endometriosis
Mutation research ·doi:10.1016/j.mrfmmm.2018.12.003
article 2018
The presence of KRAS, PPP2R1A and ARID1A mutations in 101 Chinese samples with ovarian endometriosis
Mutation research ·doi:10.1016/j.mrfmmm.2018.03.001
article 2017
Elevated plasma levels of lysophosphatidic acid and aberrant expression of lysophosphatidic acid receptors in adenomyosis
BMC women's health ·doi:10.1186/s12905-017-0474-z

BACKGROUND: Given the important roles of the receptor-mediated lysophosphatidic acid (LPA) signaling in both reproductive tract function and gynecological cancers, it will be informative to investigate the potential role of LPA in the devel…

article 2016
Downregulation of DNA methyltransferase 3 alpha promotes cell proliferation and invasion of ectopic endometrial stromal cells in adenomyosis
Gene ·doi:10.1016/j.gene.2016.12.011
article 2015
Serum metabolic profiling study of endometriosis by using wooden-tip electrospray ionization mass spectrometry
·doi:10.1039/c5ay01312g

A high throughput metabolite fingerprinting tool based on WT-ESI-MS has been established for the serum metabolic profiling study of endometriosis with little sample pre-treatment, no chromatography and instrument cycle times of less than 5 …

article 2015
Tanshinone IIA inhibits the proliferation, migration and invasion of ectopic endometrial stromal cells of adenomyosis via 14-3-3ζ downregulation
Archives of gynecology and obstetrics ·doi:10.1007/s00404-015-3766-2