Martin Knöfler

No ORCID on file · 4 papers in corpus · active 2007-2010

Study types

  • article 3
  • review 1

Condition tags

  • endometriosis 3
  • infertility 1
article 2010
Administration of βHCG leads to dose-dependent changes of gene expression signature of endometriotic stromal cells
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2010.01.010

Preliminary studies have shown that systemic beta-human chorionic gonadotrophin (betaHCG) therapy alleviates endometriosis-related chronic pelvic pain. The underlying mechanism, however, is completely unknown. This study has investigated th…

review 2010
Wnt signalling in implantation, decidualisation and placental differentiation--review
Placenta ·doi:10.1016/j.placenta.2010.07.011

The family of secreted Wingless ligands plays major roles in embryonic development, stem cell maintenance, differentiation and tissue homeostasis. Accumulating evidence suggests that the canonical Wnt pathway involving nuclear recruitment o…

article 2007
Effect of highly purified human chorionic gonadotropin preparations on the gene expression signature of stromal cells derived from endometriotic lesions: potential mechanisms for the therapeutic effect of human chorionic gonadotropin in vivo
Fertility and sterility ·doi:10.1016/j.fertnstert.2007.02.006

ObjectiveTo investigate alterations in the overall gene expression profile of endometriosis-derived stroma with increasing concentrations of hCG by using the Affymetrix GeneChip U133 Set.DesignIn vitro study.SettingAcademic research institu…

article 2007
Human chorionic gonadotrophin attenuates NF-κB activation and cytokine expression of endometriotic stromal cells
Molecular human reproduction ·doi:10.1093/molehr/gam032

Recently, a clinical study provided evidence that treatment of endometriotic women with human chorionic gonadotrophin (hCG) alleviates disease-related pain and sleeplessness suggesting therapeutic effects of the hormone. Since endometriosis…