Saleh L

ORCID: 0009-0002-8212-4535 · 6 papers in corpus
article 2019
Associations Between Natural Physiological and Supraphysiological Estradiol Levels and Stress Perception
Frontiers in psychology ·doi:10.3389/fpsyg.2019.01296

Stress is a risk factor for impaired general, mental and reproductive health. The role of physiological and supraphysiological estradiol concentrations in stress perception and stress processing is less well understood. We therefore, conduc…

2017
Lack of Associations between Female Hormone Levels and Visuospatial Working Memory, Divided Attention and Cognitive Bias across Two Consecutive Menstrual Cycles.
Frontiers in behavioral neuroscience ·doi:10.3389/fnbeh.2017.00120

Background: Interpretation of observational studies on associations between prefrontal cognitive functioning and hormone levels across the female menstrual cycle is complicated due to small sample sizes and poor replicability. Methods: This…

article 2010
Administration of βHCG leads to dose-dependent changes of gene expression signature of endometriotic stromal cells
Reproductive BioMedicine Online ·doi:10.1016/j.rbmo.2010.01.010

Preliminary studies have shown that systemic beta-human chorionic gonadotrophin (betaHCG) therapy alleviates endometriosis-related chronic pelvic pain. The underlying mechanism, however, is completely unknown. This study has investigated th…

2008
Human chorionic gonadotropin stimulates trophoblast invasion through extracellularly regulated kinase and AKT signaling.
Endocrinology ·doi:10.1210/en.2007-1282

Chorionic gonadotropin (CG) is indispensable for human pregnancy because it controls implantation, decidualization, and placental development. However, its particular role in the differentiation process of invasive trophoblasts has not been…

article 2007
Effect of highly purified human chorionic gonadotropin preparations on the gene expression signature of stromal cells derived from endometriotic lesions: potential mechanisms for the therapeutic effect of human chorionic gonadotropin in vivo
Fertility and sterility ·doi:10.1016/j.fertnstert.2007.02.006

ObjectiveTo investigate alterations in the overall gene expression profile of endometriosis-derived stroma with increasing concentrations of hCG by using the Affymetrix GeneChip U133 Set.DesignIn vitro study.SettingAcademic research institu…

article 2007
Human chorionic gonadotrophin attenuates NF-κB activation and cytokine expression of endometriotic stromal cells
Molecular human reproduction ·doi:10.1093/molehr/gam032

Recently, a clinical study provided evidence that treatment of endometriotic women with human chorionic gonadotrophin (hCG) alleviates disease-related pain and sleeplessness suggesting therapeutic effects of the hormone. Since endometriosis…