Hua Zhang

Early detection of asymptomatic ovarian cancer (asym-OC) remains a critical challenge, the failure of which underlies its high mortality. Performing serum peptidomic profiling of 843 participants in the cohort SOCFCP, we distill 1,081 initi…

BACKGROUND: Previous studies have shown a correlation between ABO blood type and the occurrence of certain diseases. However, there is limited research on the potential association between ABO blood group and polycystic ovary syndrome (PCOS…

BACKGROUND: The utilization of a double trigger, involving the co-administration of gonadotropin-releasing hormone agonist (GnRH-a) and human chorionic gonadotropin (hCG) for final oocyte maturation, is emerging as a novel approach in gonad…

BACKGROUND: Endometriosis is a common gynecological disease that affects approximately 5 %∼10 % of reproductive-aged women. Zinc (Zn), selenium (Se), copper (Cu), cobalt (Co) and molybdenum (Mo) are essential trace elements and are very imp…

BACKGROUND: To identify incidence and underlying risk factors for unsuspected placenta accreta spectrum (PAS) and compare the maternal outcomes between suspected and unsuspected cases in three large academic referral centers. METHODS: A re…

BACKGROUND: Although autoimmune abnormalities are common in patients with endometriosis, it is unknown whether patients with endometriosis have a higher risk of developing antiphospholipid syndrome (APS). METHODS: We conducted a retrospect…

Objectives: The effect of telomerase inhibitor BIBR1532 on endometriotic cells was investigated to explore the inhibitory effect of targeting telomerase on endometriosis. Design: In vitro primary cell culture study. Participants/Materials: …

Objectives: The effect of telomerase inhibitor BIBR1532 on endometriotic cells was investigated to explore the inhibitory effect of targeting telomerase on endometriosis. Design: In vitro primary cell culture study. Participants/Materials: …

Objectives: The effect of telomerase inhibitor BIBR1532 on endometriotic cells was investigated to explore the inhibitory effect of targeting telomerase on endometriosis. Design: In vitro primary cell culture study. Participants/Materials: …

Objectives: The effect of telomerase inhibitor BIBR1532 on endometriotic cells was investigated to explore the inhibitory effect of targeting telomerase on endometriosis. Design: In vitro primary cell culture study. Participants/Materials: …

BACKGROUND: Empirical treatment was introduced when pathological or microbiological results of tuberculosis (TB) were not available. This report was designed to evaluate an algorithm based on empirical treatment in defining tuberculous pleu…

BACKGROUND: It is currently unknown whether patients with a fever after controlled ovulation during egg retrieval could increase the risk of pelvic infection or not, and fever itself may affect endometrial receptivity or embryo quality with…

Catalpol is the main active ingredient of an extract from Radix rehmanniae, which in a previous study showed a protective effect against various types of tissue injury. However, a protective effect of catalpol on uterine inflammation has no…

BACKGROUND: There is limited literature investigating the effects of body mass index (BMI) and androgen level on in vitro fertilization (IVF) outcomes with a gonadotropin-releasing hormone (GnRH)-antagonist protocol in polycystic ovary synd…

AIM: Abnormal uterine bleeding (AUB) occurs in 10-30% of women of reproductive age and up to 61% of cirrhotic women. We evaluated the efficacy and safety of endometrial ablation (NovaSure therapy) for AUB in cirrhotic women. METHODS: This …

Objective: To study the influence of mirena treatment on uterine blood flow dynamics and \nserum related indexes of patients with uterine adenomyosis. Methods: A total of 58 patients \nwith uterine adenomyosis who were treated in our hospit…

Endometriosis(EMs) is an estrogen-dependent disease characterized by extrauterine implantation and ectopic growth of endometrium and it’s a common disease of women of reproductive age.The invasive implantation of ectopic endometrium is a co…

OBJECTIVE: To observe the clinical therapeutic effect of acupuncture combined with acupoint sticking therapy for treatment of dysmenorrhea caused by endometriosis, and to probe into the best therapy for this kind of disease. METHODS: Seven…

Objective:To discuss the diagnosis and treatment of abdomincal scar endometriosis.Methods:Retrospectively analyzed clinic data of 8 case in our hospital.Results:Pathological results indicated all patients had abdomincal scar endometriosis,a…

Objective:To investigate the association of single nucleotide polymorphisms (SNPs) in VEGF gene with the risk of endometriosis.Methods:Genotypes of VEGF were analyzed by polymerase chain reaction-restriction fragment length polymorphism (PC…

Objective To observe the effect and explore the mechanism of Xiaozheng Decoction (Decoction for dissolving masses), a decoction based on the principle of invigorating blood circulation, removing stasis, reinforcing the kidney, and melting p…