Xin Li
ORCID: 0009-0004-4556-9628
· 84 papers in corpus
lab-animal
2015
BACKGROUND: Cytochrome P450 aromatase (encoded by the CYP19A1/aromatase gene) plays a critical physiologic role in endometriosis. Metformin is known to suppress prostaglandin E2 (PGE2)-induced CYP19A1 messenger RNA (mRNA) expression in huma…
review
2014
Polycystic ovary syndrome (PCOS) is a state of altered steroid hormone production and activity. Chronic estrogen exposure or lack of progesterone due to ovarian dysfunction can result in endometrial hyperplasia and carcinoma. A key contribu…
other
2014
Endometrial cancer (EC) is the most common gynecological malignancy in women and is the leading cause of cancer-related deaths worldwide. Estrogenic stimulation significantly increases endometrial cell proliferation, and both insulin resist…
diagnostic-accuracy
2013
BACKGROUND: Several peripheral proteins that might be useful for detecting the presence of ectopic pregnancy (EP) have been evaluated, but none have been proven entirely useful in the clinic. We investigated the presence and the possible ch…
review
2012
Endometriosis is a common gynecological disorder affecting mostly women of reproductive age. Its presenting symptoms include dysmenorrhea, chronic pelvic pain and infertility. There is a pressing need to develop more efficacious therapeutic…
review
2010
Etilogy of endometriosis was complex,but cultivation theory is widely accepted.The pathological changes of endometrial was ectopic endometrial cyslical bleeding and the surrounding tissue fibrosis.The growth,infiltration and hemorrhage of e…
other
2009
OBJECTIVE: To investigate the expression of integrin beta3 and osteopontin (OPN) in eutopic and ectopic endometrium of adenomyosis. METHODS: From January 2007 to July 2008, the endometrium specimens were collected from 43 patients with ade…
2008
Objective To investigate the expression of progesterone receptor subtypes in adenomyosis tissues and eutopic endometrium.Methods Immunohistochemical streptavidin-biotin peroxidase was applied to compare the expressions of progesterone recep…
review
2001
Endometriosis is defined as endometriotic tissues growing outside the uterine cavity.Essential for its survival is the generation and maintenance of an extensive blood supply both within and surrounding the ectopic tissue.The pathogenesis a…