Shaofen Zhang

No ORCID on file · 12 papers in corpus · active 2009-2024

Study types

  • article 10
  • rct 2

Condition tags

  • endometriosis 9
  • adenomyosis 4
  • dysmenorrhea 3
  • chronic_pelvic_pain 3
  • dyspareunia 2
rct 2024
Efficacy and Safety of Sanjie Analgesic Capsule in Patients with Endometriosis-Associated Pain: A Multicenter, 3:1 Randomized, Double-Blind, Placebo-Controlled Trial
Chinese journal of integrative medicine ·doi:10.1007/s11655-024-3756-y

OBJECTIVE: To assess the efficacy and safety of Sanjie Analgesic Capsule (SAC) in Chinese patients with endometriosis-associated pain. METHODS: This was a multicenter, randomized, double-blind, placebo-controlled trial conducted at 15 cent…

article 2015
Efficacy of GnRHa plus Yasmin or Mirena in the treatment of polycystic ovarian syndrome with a typical hyperplasia in patients with adenomyosis accompanied with dysmenorrhea
article 2015
Initiation of GnRH agonist treatment on 3-5 days postoperatively in endometriosis patients: a randomized controlled trial
Journal of clinical pharmacology ·doi:10.1002/jcph.485

Seventy patients with stage III or IV endometriosis were randomly assigned to 2 groups after conservative surgery. Group O (n = 35) received 3 cycles of a 28-day gonadotropin-releasing hormone agonist (GnRH-a) treatment (goserelin, 3.6 mg) …

article 2014
[Expression of nerve growth factor produced by ectopic endometrium from patients with adenomyosis and its relationship with pain scales and innervation].
Zhonghua fu chan ke za zhi

OBJECTIVE: To investigate the expression of nerve growth factor (NGF) in the ectopic endometrium in adenomyosis patients, and explore the relationship between NGF expression and innervation or pain scales. METHODS: From Mar. 2009 to Oct. 20…

article 2014
Human Adenomyosis Endometrium Stromal Cells Secreting More Nerve Growth Factor
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719114561559
article 2013
Oral continuous combined 0.5 mg estradiol valerate and 5 mg dydrogesterone as daily add-back therapy during post-operative GnRH agonist treatment for endometriosis in Chinese women.
International journal of clinical and experimental medicine

OBJECTIVE: To evaluate the lowest effective dose of combined estrogen and progestogen (E(2)+P) add-back therapy during post-operative gonadotropin-releasing hormone agonist (GnRHa) treatment for endometriosis in Chinese women. STUDY DESIGN:…

article 2013
The incidence and characteristics of uterine bleeding during postoperative GnRH agonist treatment combined with estrogen-progestogen add-back therapy in endometriosis patients of reproductive age.
International journal of clinical and experimental medicine

To evaluate the incidence and characteristics of uterine bleeding during postoperative gonadotropin-releasing hormone agonist (GnRHa) treatment combined with the lowest effective dose of estrogen-progestogen add-back therapy in Chinese wome…

article 2011
steve bAccumulation of nerve growth factor and its receptors in the uterus and dorsal root ganglia in a mouse model of adenomyosis
Reproductive biology and endocrinology : RB&E ·doi:10.1186/1477-7827-9-30

BACKGROUND: Adenomyosis is a common gynecological disease, which is accompanied by a series of immunological and neuroendocrinological changes. Nerve growth factor (NGF) plays a critical role in producing pain, neural plasticity, immunocyte…

article 2010
[Clinical efficacy and safety of gonadotropin releasing hormone agonist combined with estrogen-dydrogesteronea in treatment of endometriosis].
Zhonghua fu chan ke za zhi

OBJECTIVE: To compare clinical effect of gonadotropin releasing hormone agonist (GnRH-a) alone and GnRH-a combined with low-dose dydrogesteronea and estradiol valerate on sex hormone, hypoestrogenic symptoms, quality of life and bone minera…

article 2009
[Effects and safety of gonadotrophin-releasing hormone agonist combined with estradiol patch and oral medroxyprogesterone acetate on endometriosis].
Zhonghua fu chan ke za zhi ·doi:10.3760/cma.j.issn.0529-567x.2009.07.007

OBJECTIVE: To evaluate effects and safety of gonadotrophin-releasing hormone agonist (GnRH-a) combined with transdermal estradiol and medroxyprogesterone acetate in the treatment of endometriosis. METHODS: From January 1st, 2007 to July 31s…

rct 2009
Effects of estrogen replacement therapy on estrogen receptor expression and immunoregulatory cytokine secretion in surgically induced menopausal women
Journal of reproductive immunology ·doi:10.1016/j.jri.2009.02.008

To investigate the effect of oral and transdermal estrogen replacement therapy (ERT) on the expression of different estrogen receptor (ER) subtypes and the secretion of immunoregulatory cytokines, we performed a clinical investigation on pr…

article 2009
Medical treatment for refractory endometriosis.

Patients with refractory endometriosis sometimes don't respond to conventional medical treatment regimens because of the refractoriness. Clinical trials and documents suggest that GnRHa has good clinical effect. Especially in patients with …